Of the errors of such as have descended and applied themselves to experience, and attempted to induce knowledge upon particulars. That they have not had the resolution and strength of mind to free themselves wholly from Anticipations, but have made a confusion and intermixture of Anticipations and observations, and so vanished. That if any have had the strength of mind generally to purge away and discharge all Anticipations, they have not had that greater and double strength and patience of mind, as well to repel new Anticipations after the view and search of particulars, as to reject old which were in their mind before; but have from particulars and history flown up to principles without the mean degrees, and so framed all the middle generalities or axioms, not by way of scale or ascension from particulars, but by way of derivation from principles; whence hath issued the infinite chaos of shadows and notions, wherewith both books and minds have been hitherto, and may be yet hereafter much more pestered. That in the course of those derivations, to make them yet the more unprofitable, they have used when any light of new instance opposite to any assertion appeared, rather to reconcile the instance than to amend the rule. That if any have had or shall have the power and resolution to fortify and inclose his mind against all Anticipations, yet if he have not been or shall not be cautioned by the full understanding of the nature of the mind and spirit of man, and therein of the seats, pores and passages both of knowledge and error, he hath not been nor shall not be possibly able to guide or keep on his course aright. That those that have been conversant in experience and observation have used, when they have intended to discover the cause of any effect, to fix their consideration narrowly and exactly upon that effect itself with all the circumstances thereof, and to vary the trial thereof as many ways as can be devised; which course amounteth but to a tedious curiosity, and ever breaketh off in wondering and not in knowing; and that they have not used to enlarge their observation to match and sort that effect with instances of a diverse subject, which must of necessity be before any cause be found out. That they have passed over the observation of instances vulgar and ignoble, and stayed their attention chiefly upon instances of mark; whereas the other sort are for the most part more significant and of better height and information. That every particular that worketh any effect is a thing compounded (more or less) of diverse single natures, (more manifest and more obscure,) and that it appeareth not to whether of the natures the effect is to be ascribed, and yet notwithstanding they have taken a course without breaking particulars and reducing them by exclusions and inclusions to a definite point, to conclude upon inductions in gross, which empirical course is no less vain than the scholastical.