“_On admission_, enormous œdema, including fingers, hand, entire right arm, cervical region on the same side, and the anterior face of the thorax, nearly as far as the inner margin of the false ribs. This œdema was not very painful, though fairly tense, yielding but slightly to pressure. In the affected region the skin was cold, of a dull livid colour, with a few ecchymosed patches. In the bitten finger, a small wound with no special characteristics. “General condition bad; the child was unable to stand. He was indifferent to what was passing around him, merely groaning a little when examined. The pulse was feeble, thin, and easily compressible; it was also very irregular. The extremities were cold. Lungs: nothing abnormal on auscultation, rapidly performed, it is true. Respiration, however, was distinctly accelerated, 30 per minute. Temperature not taken on admission. No urine passed since the accident. “The patient’s condition being so alarming, not to say desperate, we thought it almost useless to have recourse to Calmette’s method, more especially since at least seven hours had already elapsed since the child was bitten. Nevertheless we gave a hypodermic injection of 20 c.c. of Calmette’s serum. At the same time the wound was crucially incised, and bathed with a 1 in 1,000 solution of permanganate of potash, after which a damp dressing was applied to the whole of the swollen limb. The patient was put to bed, and kept warm. He was given an injection of 50 centigrammes of caffeine, and 300 grammes of artificial serum. In the evening the temperature was 36·8° C. “May 27.--General condition more satisfactory; pulse still weak, but less irregular. Persistence of dyspnœa, explained by a series of small râles at the bases of both lungs. This morning the little patient passed his urine, about 200 grammes. He is more lively, and replies better to any questions addressed to him. “May 28.--The improvement continues; the dyspnœa has almost entirely disappeared; only a few râles are still heard at the extreme base. The pulse is stronger and remains regular. The secretion of urine gradually reappears. The temperature of the extremities has become normal. “On May 29 and following days the œdema continued to diminish, and had totally disappeared eight or ten days later. “Recovery was complete by about June 15. The child was discharged on June 23, 1904. “It seemed to us worth while to report this case, in order to emphasise the conclusion that forces itself upon us, namely that in all cases of bites from poisonous snakes an injection of Calmette’s serum should be given, without considering the efficacy of this therapeutic agent as being rendered doubtful by the length of time that may have elapsed since the bite was inflicted.