“At 9.30, after taking the usual antiseptic precautions, we gave an injection of Calmette’s antivenomous serum, from a bottle dated December 26, 1896. Not having any hypochlorite of calcium at our disposal, we washed the wound with a 1 in 60 solution of hyposulphite of soda, and applied a dressing of carbolic gauze. An hour later the patient was taken to Saint Pierre in a carriage. Temperature 37·2° C. No vomiting, or tetanic phenomena. In the afternoon the pain was less acute, and the œdema seemed to have diminished a little. Mercurial ointment rubbed in. “Four days later the patient, being cured without having had the least rise of temperature, proceeded to the country. “This case is interesting, since a single dose of antivenomous serum (20 grammes), injected two hours and a half after the accident, sufficed to cure a young man bitten by a _Trigonocephalus_ measuring 1 metre 20 cm. in length.” M.--Crotalus horridus. XXXVIII.--Case recorded by Dr. P. Renaux, of Piriapolis, Uruguay (_La Tribuna popular_, Piriapolis, December 14, 1898). Silverita, aged 20, bitten in the ankle by a _Crotalus_, on December 7, 1898. Symptoms of serious intoxication. Treated with a dose of antivenomous serum, injected half in the right flank, half in the left. Recovery. II.--A FEW NOTES AND OBSERVATIONS RELATING TO DOMESTIC ANIMALS BITTEN BY POISONOUS SNAKES AND TREATED WITH SERUM. A.--Naja haje. XXXIX.--Case reported by Dr. Maclaud, of Konakry, French Guinea. “A hound belonging to the Governor of Konakry was bitten in the ear by a black _Naja_. A similar accident happened last year, and the animal died on the fifth day. In the present case, serious phenomena had already manifested themselves: depression, convulsions, and great swelling of the entire head and anterior portion of the trunk. A dose of 10 c.c. was injected at three different points: in the flank, neck, and cellular tissue of the injured ear. Improvement was almost immediate. On the following day the animal recovered its appetite, and two days later was completely cured.” XL.--Case reported by Dr. Marotte, of Konakry.