Veterinary Medicines, Their Actions, Uses and DoseKorinek, George Franklyn
Science
Veterinary Medicines, Their Actions, Uses and Dose
Korinek, George Franklyn
Veterinary drugs
OPIUM
DERIVATION.--The concrete, milky exudate obtained by incising the unripe
capsules of Papaver somniferum Linne, and yielding in its normal, moist
condition, not less than nine per cent of crystallized morphine when
assayed by the official process. Opium is imported from Turkey, Asia
Minor, Persia, India and Egypt. The Smyrna, or Turkey opium, is the more
common variety used in the United States. It occurs in irregular,
globular masses, covered with poppy leaves and capsules of a species of
dock, weighing from one-half to one pound.
PROPERTIES.--In irregular, flattened, more or less rounded masses of
variable size, externally grayish-brown, covered with particles of poppy
leaves and with occasional fruits of a species of Rumex; more or less
plastic when fresh, but becoming hard on keeping; internally dark brown,
somewhat lustrous; odor strong, narcotic; taste bitter and
characteristic. It yields its medical properties to water, alcohol and
dilute acids, forming dark brown solutions. Ether extracts its
principles in part.
CONSTITUENTS.--There are about nineteen or twenty alkaloids derived from
opium, but only a few are of any importance so far as their medical
value is concerned.
DOSE.--Of the crude opium--Horses, 1 to 2 dr.; cattle, 2 to 4 dr.;
sheep, 10 to 30 gr.; pigs, 5 to 10 gr.; dogs, ¹⁄₂ to 2 gr.
PREPARATIONS
OPII PULVIS--POWDERED OPIUM
This is opium dried at a temperature not exceeding 85° C. (185° F.) and
powdered and should not contain less than 12 per cent nor more than
12¹⁄₂ per cent morphine.
DOSE.--Horses, ¹⁄₂ to 1¹⁄₂ dr.; cattle, 1 to 3 dr.; sheep, 5 to 30 gr.;
pigs, 5 to 15 gr.; dogs, ¹⁄₄ to 3 gr.
EXTRACTUM OPII--EXTRACT OF OPIUM
Composed of powdered opium, 100 parts; distilled water, 1000 parts;
sugar of milk, a sufficient quantity. Made by trituration, filtration
and evaporation. Assayed to contain 20 per cent of morphine.
DOSE.--Horses, ¹⁄₂ to 1 dr.; cattle, 1 to 2 dr.; sheep, 5 to 15 gr.;
pigs, 3 to 10 gr.; dogs, ¹⁄₄ to 2 gr.
PULVIS IPECACUANHAE ET OPII--POWDER OF IPECAC AND OPIUM--DOVER’S POWDER
Composed of ipecac, 10 parts; powdered opium, 10 parts; sugar of milk,
80. The most diaphoretic and expectorant compound of opium.
DOSE.--Horses, ¹⁄₂ to 1 oz.; dogs, 2 to 12 gr.
TINCTURA IPECACUANHAE ET OPII--TINCTURE OF IPECAC AND OPIUM--LIQUID
DOVER’S POWDER
Composed of tincture of deodorized opium 100, evaporated to 80, fluid
extract of ipecac 10, diluted alcohol sufficient quantity to make 100.
DOSE.--Horses, ¹⁄₂ to 1 oz.; dogs, 3 to 12 m.
TINCTURA OPII--TINCTURE OF OPIUM
Popularly Known as Laudanum
Composed of granulated opium, 100 parts; alcohol, 400 parts; water, 400
parts; diluted alcohol to make 1000. Made by trituration, maceration
with precipitated calcium phosphate and percolation. Assayed and
standardized to contain between 1.2 and 1.25 gm. of morphine in 100 c.
c.
DOSE.--Horses, 1 to 2 oz.; cattle, 2 to 3 oz.; sheep and pigs, 2 to 4
dr.; dogs, 3 to 20 m.
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