Veterinary Medicines, Their Actions, Uses and DoseKorinek, George Franklyn
Science
Veterinary Medicines, Their Actions, Uses and Dose
Korinek, George Franklyn
Veterinary drugs
ACTIONS.--Potassium acetate and citrate are the least irritant to the
stomach of all the potassium salts. They are neutral and have no action
on the gastric juice: are not antacid. They are changed into the
carbonate of potassium and as such circulate in the blood. Are powerful
direct diuretics, stimulate the renal cells direct and increase both the
water and the solids of the urine, also diaphoretic; the citrate more
than the acetate. They have a slight depressing action on the heart, and
slightly expectorant.
USES.--Potassium acetate and citrate are indicated in irritation or
inflammation of the kidneys and bladder and cause absorption of
exudations (pleural effusion, for example) through their diuretic power.
They are sometimes prescribed in fever on account of slight diaphoretic
and powerful diuretic properties. They also stimulate bronchial
secretions and make it thinner and are recommended accordingly in
bronchitis. They are used in gouty conditions, Bright’s disease, fevers
of all kinds, azoturia, dropsical conditions, pleurisy, ascites oedema
of the legs, sheath, udder, etc., combined with tonics, as iron, etc.
POTASSII BROMIDUM--POTASSIUM BROMIDE
DERIVATION.--Potassium bromide may be obtained by adding a slight excess
of bromide to a strong solution of potassium hydroxide, evaporating the
potassium bromide and bromate to dryness, decomposing the bromate by
fusing the mixture with charcoal and purifying the crystallization.
PROPERTIES.--Colorless, or white, cubical crystals, or granules;
odorless and having a strong saline taste. Permanent in the air. Soluble
in about fifteen parts of water and in about one hundred and eighty
parts of alcohol.
SODII BROMIDUM--SODIUM BROMIDE
DERIVATION.--Sodium bromide may be obtained in the same manner as
potassium bromide, sodium hydroxide being used in place of potassium
hydroxide.
PROPERTIES.--It occurs in colorless or white, cubical crystals, or a
white, granular powder, odorless and having a saline, bitter taste. The
salt absorbs moisture from the air without deliquescing. Soluble in one
and seven-tenths parts of water and in twelve and a half parts of
alcohol.
ACTION OF POTASSIUM AND SODIUM BROMIDE.--They are distinguished
depressants of the cerebral and spinal functions, also hypnotic,
anaphrodisiac, antispasmodic and alterative. The bromide of potash, like
all other potassium salts, is especially a cardiac and muscular
paralyzant. They are very diffusible and slowly eliminated; long
continued doses produce gastric catarrh. They reduce the number of
respirations and the heart’s action and force; lessen activity of brain
cells, producing sleep; diminish sensibility of peripheral nerves,
causing anesthesia of the skin and mucous membrane.
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