His second son, Antonio Francesco d'Ornano, met, like his father, a violent end. It was he with whom the unhappy Vannina fled from Marseilles to Genoa, and who was with her when she was murdered by her enraged husband. Antonio Francesco lived, like his brother, at the court of France. Young, of a fiery temperament, and with a strong desire to see the world, he sought and obtained leave to accompany the ambassador of Henry III. to Rome. One day, at cards, a quarrel arose between him and some French gentlemen of the embassy, among whom one M. de la Roggia took the lead. The impetuous Corsican let fall some insulting words; but the Frenchman restrained his anger and concealed his desire for revenge, and the youthful Ornano suspected nothing. A riding-party was soon after formed for a visit to the Colosseum. Here Ornano, after his Italian friends had left him, remained alone with his servant and twelve Frenchmen, half of the number on horseback, and half on foot. M. de la Roggia invited him to dismount and accompany him into the Colosseum. Ornano agreed; but had hardly dismounted from his horse, before the treacherous Frenchmen—those who were mounted as well as those on foot—fell upon him. Though bleeding from several wounds, Ornano defended himself against this unequal force with heroic courage. Setting his back to a pillar of the Colosseum, he made a bold and vigorous stand with his sword, till he was overpowered and fell. The murderers fled, leaving him weltering in his blood. Mortally wounded, he was carried to his own house, where he died on the following day. This event took place in the year 1580. He was never married, and left no descendants.