Pain anywhere in any zone may be overcome more quickly by pressure with an applicator, or with cautery contact at certain points throughout the corresponding zone or zones in the mouth, pharynx, epipharynx and nose; but the finger and toe pressures may be relied upon very often. What applies to one zone applies to all. Pressures average from one-half minute to four minutes or longer, depending upon the susceptibility of the patient. Heat or cold waves in varying degrees, depending upon the solution or instruments used, may often be dispatched to the extremities from the mouth, nose, etc., and similar waves of heat or cold will manifest themselves in the mouth, nose and pharynx of susceptible individuals from pressure or contact on the extremities. The most susceptible patients will describe them accurately. For instance, if a cotton tipped probe be dipped in camphor solution, or alcohol, the patient will describe the sensation reflected along the particular zone pressed as “cold.” If in nitrate of silver, or trichloracetic acid, he says it is “hot.” The majority of patients say that, while they are unable to detect these sensations--only extra-susceptible individuals have this faculty,--their pain is disappearing, or has already disappeared. Patients who are most susceptible to pressure or contact will trace heat or cold from an individual hair of the head, or an eyelash, to the margin of the finger-nail or toe-nail, and if a hair or eyelash be quickly pulled out, the sensation of numbness is often quickly registered beneath the finger-nail or toe-nail of the invaded zone. But to give these delicate results the subjects must be very responsive. Pressure or contact upon the occlusal, or biting, edges of the teeth affect the innermost parts of practically every bone in the body. We believe that the teeth, being the most accessible, are the natural guardians of the bones throughout the body. The heat waves from the application of a fine point cautery contact on the biting edges of the teeth, are dispatched through the centers of all bones, and their therapeutic, or curative effect is disseminated through the bones and tissue in the zones treated. Naturally, the therapeutic effect is less marked as the surface of the body is approached. Pressure or contact on the anterior surface of the teeth affects the anterior surface of the bones in the anterior sections of bones, and to a greater or less extent the tissues of the same zones in the corresponding sections. Pressure or contact on the posterior surface of the teeth affect the posterior surface of the bones in the posterior sections of zones treated, and to a greater or less extent the tissues of the same zones in the corresponding sections.