16. Of all syllogistic figures, the first is the best adapted to science, since the arithmetician, geometrician, and lastly all those who demonstrate any effect from its proper cause, fabricate their reasonings according to this figure. For the middle figure is seldom used, because only adapted to a few occasions: and since the knowledge of the _why_ is of all others the most important, which is alone obtained by this figure: hence, in the pursuit of science, it is always preferred before the rest. Besides, it is equally accommodated to the knowledge of final causes; to which it alone tends: for it composes definitions from words universal, and affirmative. In the second figure, a complex negative is conceived; and in the last, a particular one. Add to this, that mediate propositions are no other ways reducible to immediate ones than by this figure, in which the mediate proposition tends, by a continued series, to that which is immediate. But the second does not conclude affirmatively, nor the last universally; from whence it appears, that a mediate proposition can never become immediate by these figures: not that all affirmative propositions are immediate ones, since some negatives are of this kind; for all propositions are equally immediate, which cannot be confirmed by syllogism; and such are those negatives, of whose terms it is impossible any genus can be affirmed. Thus the proposition, _no substance is quality_, is an immediate negative of this kind, whose terms are two of the most universal genera of things.