"A happy new year to my dear Charlotte and to all my dear friends at home! I feel that I should be happy to spend today with you, but though absent, still, in spirit, I am with you, for my thoughts have dwelt all the morning with my dear friends in St. Louis. We left Louisville last night at seven o'clock and are now passing "Rising Sun," a village in Indiana, thirty-five miles below Cincinnati, which we hope to reach by dinner time. I saw no one in Louisville that we knew. Mr. B. was not there and I made no inquiries about his family, as I do not know his partner, Mr. G., and we remained there but a few hours. I read, this morning, the 46th chapter of Isaiah, and, from the fact of this being new year's day, my mind has been carried to the goodness of God to usward, in granting all the blessings we enjoy:--His infinite greatness, wisdom and mercy. I feel greater reliance on the atonement of our divine Saviour, and a full assurance that if we are faithful unto the end, we shall reap a crown of immortality and be forever blessed by His presence. Let us then, dear Charlotte, endeavor to realize more than we ever yet have done the reality of eternal things, and fix our minds more on the attainment of the salvation, not only of our own souls, but of all those who are near and dear to us. Let us "seek first the kingdom," feeling assured that all things else will be given us that is best for us. I am satisfied that love to God will purify our souls, and make us better fitted for the trials of this world, and will ensure eternal happiness to us hereafter. "I send you a kiss, which you must share with our dear little girl, not forgetting aunt Loo's share. When you write, let me know how the boys (my brothers Taylor and Wm.) get on at St. Charles, and the news generally of all the family." CINCINNATI. "I have just called on Dr. Drake and family, and find them very pleasant people. We stay here but a few hours, and leave for Wheeling, at 8 o'clock to-night. Remember me to mother, and to all our dear friends at home. Yours truly, JOS. CHARLESS."