For a decided case of cholera, it is best to begin with half a teaspoonful of the mixture; which, by the by, should be sucked down by the patient very slowly, in order to have it remain on the stomach. No time should be wasted listening to the old story of working off a bowel complaint; few are the adults that ever have survived the experiment, much less the weakly infant. Deaths from cholera cannot possibly be so numerous in consequence of the discharges having been checked too soon, for the usual precaution is not to arrest them; so they are let to go on increasing, till all hopes of contracting the vessels are vain. It would be well in all cases before administering Mixture No. 1, to fill a flannel bag with hops, wring it out of warm, salt water and lay it over the chest and belly, re-wetting every two hours; this done will alone sometimes prove successful. When the mouth remains dry and hot, a little cool water, sucked slowly from a spoon, does seem to revive the little sufferer, and I have no reason to doubt its efficacy in abating the suffering, if not the disease. Stimulant astringents are what is needed after the passages are checked. The least mite of Nature’s stimulant—common salt—laid on the back part of the tongue, will excite a flow of saliva, and greatly assist in removing a sort of hair-worm which has been noticed to infest the throat in some patients. When there is a continuance of vitality, and the passages continue to be green, or tinged with blood, and external cooling applications, as of flaxseed poultices, have been well tried, an effort should be made to stimulate the liver; this is very likely to be the case where the age and constitution of the child is sufficient to permit the disease to run on for quite a while. Hydrargium chloridum-calomel, is sometimes the most reliable drug that can be used to correct that. This drug is unsafe in the hands of the inexperienced, but quick and safe when under the guidance of medical skill. The dose for a child six months old should never exceed one-sixteenth of a grain, or one grain in sixteen hours, followed by a sip of warm milk.