The conclusion of a new volume of a work, involving so much care, labour and responsibility, as are necessarily attached, at the present day, to a Journal of Science and the Arts, naturally produces in the mind, a state of not ungrateful calmness, and a disposition, partaking of social feeling, to say something to those who honour such a production, by giving to it a small share of their money, and of their time. The Editor’s first impression was, that the sixth volume should be sent into the world without an introductory note, but he yields to the impulse already expressed, and to the established usages of respectful courtesy to the public, which a short preface seems to imply. He has now persevered almost five years, in an undertaking, regarded by many of the friends whom he originally consulted, as hazardous, and to which not a few of them prophetically alloted only an ephemeral existence. It has been his fortune to prosecute this work without, (till a very recent period,) returns, adequate to its indispensable responsibilities;—under a heavy pressure of professional and private duty; with trying fluctuations of health, and amidst severe and reiterated domestic afflictions. The world are usually indulgent to allusions of this nature, when they have any relation to the discharge of public duty; and in this view, it is with satisfaction, that the Editor adds, that he has now to look on formidable difficulties, only in retrospect, and with something of the feeling of him, who sees a powerful and vanquished foe, slowly retiring, and leaving a field no longer contested. This Journal which, from the first, was fully supplied with original communications, is now sustained by actual payment, to such an extent, that it may fairly be considered as an established work; its patronage is regularly increasing, and we trust it will no longer justify such remarks as some of the following, from the pen of one of the most eminent scientific men in Europe. “Nothing surprises me more, than the little encouragement which your Journal,” (“which I always read with very great interest, and of which I make great use,”) “experiences in America—this must surely arise from the present depressed condition of trade, and cannot long continue.” Six years more of uninterrupted editorial work passed by, the sixteenth volume was completed, and the editor was now in a position to review the whole situation up to 1829. This preface (dated July 1, 1829), which is quoted nearly in full, cannot fail to be found particularly interesting and from several standpoints, not the least for the insight it gives into the writer’s mind. It is also noteworthy that at this early date it was found possible to pay for original contributions, a privilege far beyond the means of the editor of to-day. When this Journal was first projected, very few believed that it would succeed.