“Conveyance by air can be easily rendered as safe as by water or land, and more cheap and speedy, while the universal and uniform diffusion of the air over every portion of the earth, will render aërial navigation preferable to any other. To carry it into effect, there needs only an immediate appeal on a sufficiently large scale, to experiment; reason has done her part, when experiment does hers, nature will not refuse to sanction the whole. Aërial navigation will present the works of nature in all their charms; to commerce and the diffusion of knowledge, it will bring the most efficient aid, and it can thus be rendered serviceable to the whole human family.” A subject of quite another character is the first discussion of the properties of chloroform (chloric ether) and its use as an anæsthetic (Guthrie, =21=, 64, 405, 1832; =22=, 105, 1832; Levi Ives, =21=, 406). Further interesting communications are given of the first analyses of the gastric juice and the part played by it in the process of digestion. Dr. William Beaumont of St. Louis took advantage of a patient who through a gun-shot wound was left with a permanent opening into his stomach through which the gastric juice could be drawn off. The results of Dr. Beaumont and of Professor Robley Dunglison, to whom samples were submitted, are given in full in the life of Beaumont by Jesse S. Myer (St. Louis, 1912). The interest of the matter, so far as the Journal is concerned, is chiefly because Dr. Beaumont selected Professor Silliman as a chemist to whom samples for examination were also submitted. An account of Silliman’s results is given in the Beaumont volume referred to (see also =26=, 193, 1834). Desiring the support of a chemist of wider experience in organic analysis, he also sent a sample through the Swedish consul to Berzelius in Stockholm. After some months the sample was received and it is interesting to note in a perfectly fresh condition; it is to be regretted, however, that the Swedish chemist failed to add anything to the results already obtained in this country (=27=, 40b, 1835). The above list, which might be greatly extended, seems to leave little ground for the implied criticism replied to by Silliman as follows (=16=, p. v, 1829): A celebrated scholar, while himself an editor, advised me, in a letter, to introduce into this Journal as much “_readable_” matter as possible: and there was, pretty early, an earnest but respectful recommendation in a Philadelphia paper, that Literature, in imitation of the London Quarterly Journal of Science, &c. should be in form, inscribed among the titles of the work. _The Second, Third and Fourth Series._