By this we may see how circumspect we ought always to be, lest we interrupt the Design of Nature when she is about to expel any morbifick Matter, the ill Effects that attend it oftentimes discovering themselves after different Manners; We look upon a continued Discharge of Matter to be, as it were, a natural Evacuation, and that it’s immediate Stoppage, without other Means, being made use of to divert and evacuate it, to be succeeded by a greater Fulness and Distention of all the Vessels, as is observable upon the Suppression of the _Menses_, _Hemorrhoides_, or _insensible Transpiration_, there is this Difference to be observed that the ill Accidents that attend the Stoppage of the Discharge of Matter are not so much owing to the Distention and Plenitude of the Vessels, but according to the ill Quality of it, ’tis disposed to render the Patient feverish more or less, which is generally ushered in by Rigours, and sometimes succeeded by Spasmodic Contractions. For a further Illustration of this, we will take the liberty to relate the Case of a Man of about Forty Years of Age, who was for a considerable time incommoded in his Business, by reason of a violent Contusion he had received on the Upper-part of his Left Arm, a little below the Shoulder: After some time it was succeeded by an Apostemation, upon the opening of which I was informed, a considerable Quantity of Matter discharged, which was not of any ill Colour or Smell, the Matter continuing to make its Exit the same way for several Weeks, at length formed a _Sinus_, which might be easily traced to the Upper and Fore-part of the _Os Humeri_. The external Orifice of this was endeavoured to be dilated, but it not only put the Patient to a great deal of Pain, but pent in the Matter, and caused the contiguous Parts to tumifie very much. About this time the Axillary Glands began to swell and pain him, and by their Pressure on the Limphaticks the whole Arm became Oedematous; soon after some part of the Matter made it’s way out under the Arm, upon which it almost ceased to flow from the _Sinus_ on the upper-part of it. In short, upon this the Patient found himself very much indisposed, he lost his Appetite, was attended with Shiverings, became feverish, and at length died violently convulsed.