We are very well assured, _Sir_, that it has been a Matter of very great Surprize to several ingenious Men, to consider how the various Operations of the Body have continued to be performed, when those Parts which were so absolutely necessary to the Well-being of the Animal, have been naturally or accidentally disordered to such a degree, as to suffer a perfect Confusion of their Parts: And of this we find Variety of Instances in those Authors, who have very obligingly applied themselves to relate the Histories of deceased morbid Bodies. But that the Brain it self, which is the very Source and Principle of all Animal Functions, should, after it has undergone such a Violation as we have observed, continue several Days without incommoding the Person in the least respect, is really very remarkable; for if we do but consider what an absolute Necessity there is for a constant Supply of Animal Spirits, to empower the Parts to perform their mechanical Actions, and at the same time reflect on the Disorder and Corruption of that Part, whose Office it was to secrete a sufficient Quantity of those Spirits, we might very reasonably expect a considerable Alteration in the whole Body. One might very well think, that from the Deficiency of Spirits that would ensue, the Parts could no longer continue to perform their Actions, but must gradually lose their Power and Spring, and at length become in a manner destitute of Motion: For we can scarce perswade our selves, that Nature in this Case is so provident as to suffer the _Cerebellum_ and _Medulla Spinalis_ to filtrate the Spirits in a greater Quantity, that they might supply the Exigencies of the Body.