The Reader may easily imagine that making so small a Progress in such a time, and that at the Expence of so much Pain, I could easily prevail with my self to desist from the Undertaking, for the second Application would have been attended with the same Inconveniencies as the first, which to any Persons that entertains such a concern for his Patients as he ought to do, must be very fatiguing; in short, after this I made use of that Remedy I had elsewhere mentioned, and which from its Effect was properly enough called a _Dissolvent_, with this by the Blessing of God the _Cancerous_ Substance was consumed in about three Weeks, and a perfect Cure compleated in not many Days after, the Patient which I saw lately continuing perfectly well, it being the first Case that ever Providence directed me to the use of the Remedy in. _Hildan_ has an Observation very pertinent to what we have before related; he tells us, that the _Powder_ so much celebrated by _Penotus_, and which is much the same with that just now mentioned, being applied to a _Cancer_, was succeeded by such ill Symptoms, that it killed the Patient in a few Days. We are informed in the communicated Observations of _Riverius_, that a Foreigner extirpated a Cancer, that had began to Ulcerate in the Breast of a Woman of fifty Years of Age, by the following Application: ℞ _Arsenici_ ʒi. _Salis Armoniaci_ ℥ii. _Sublimat. crud._ ℥iiii. _Aq; Fortis_ ℥i. _These were to be distill’d to Dryness, then an equal Weight of distill’d Vinegar put thereto, which was to be distilled again, till the remaining Matter, became of the Consistance of a Paste._ The Surgeon bathed the _Cancer_ with hot Wine, and rubbed it with Cloths for some time to _irritate_ it, then he spread some of his Composition on a Bolster six times less than the _Tumour_, and applied it; in twenty four Hours time, it made an _Escar_ as large as the Swelling, so that it wholly consumed the _Cancer_; after the Separation of the _Escar_ he incarned the _Ulcer_ and cicatrized it. It is very observable, that he did not engage in this painful Process, without immediately causing a Fever, which was attended with a _Vomiting_, _Loosness_, and much Provocation of _Urine_; which Symptoms lasted two or three Days, for Nature was disordered by the destructive Quality of a venemous Remedy. _Paracelsus_, _Faber_, and some others, make mention of Arsnical Preparations, that procure but little Pain in their Operation; I had a Design of making a Trial of some of these Remedies, had I not in my Enquiries met with what was very satisfactory to me, though after knowing what I have related, I should have always cautiously avoided the use of any Remedy, in which the _Arsnick_ had not undergone such a Preparation as I should have approved of, because I am assured it may procure very mischievious Symptoms, though in Substance, it do not so much as touch the Skin, witness the _Amulets_, in which it has been the chief Ingredient, and