First, it is thought by you a sure Aphorisme in the Physickes, That the braines of all men, being naturally colde and wet, all dry and hote things should be good for them; of which nature this stinking suffumigation is, and therefore of good vse to them. Of this Argument, both the Proposition and Assumption are false, and so the Conclusion cannot but be voyd of it selfe. For as to the Proposition, That because the braines are colde and moist, therefore things that are hote and drie are best for them, it is an inept consequence: For man beeing compounded of the foure Complexions (whose fathers are the foure Elements) although there be a mixture of them all in all the parts of his body, yet must the diuers parts of our _Microcosme_ or little world within ourselves, be diuersly more inclined, some to one, some to another complexion, according to the diuersitie of their vses, that of these discords a perfect harmonie may bee made vp for the maintenance of the whole body. The application then of a thing of a contrary nature, to any of these parts is to interrupt them of their due function, and by consequence hurtfull to the health of the whole body. As if a man, because the Liuer is hote (as the fountaine of blood) and as it were an ouen to the stomache, would therefore apply and weare close vpon his Liuer and stomache a cake of lead; he might within a very short time (I hope) be susteined very good cheape at an Ordinairie, beside the cleering of his conscience from that deadly sinne of gluttonie. And as if, because the Heart is full of vitall spirits, and in perpetuall motion, a man would therefore lay a heauy pound stone on his breast, for staying and holding downe that wanton palpitation, I doubt not but his breast would bee more bruised with the weight thereof, then the heart would be comforted with such a disagreeable and contrarious cure. And euen so is it with the Braines. For if a man, because the Braines are colde and humide, would therefore vse inwardly by smells, or ontwardly by application, things of hot and drie qualitie, all the gaine that he could make thereof would onely be to put himselfe in a great forwardnesse for running mad, by ouer-watching himselfe, the coldnesse and moistnesse of our braine beeing the onely ordinarie meanes that procure our sleepe and rest. Indeed I do not denie, but when it falls out that any of these, or any part of our bodie growes to be distempered, and to tend to an extremetie, beyond the compasse of Natures temperate mixture, that in that case cures of contrary qualities, to the intemperate inclination of that part, being wisely prepared and discreetely ministered, may be both necessarie and helpefull for strengthning and assisting Nature in the expulsion of her enemies: for this is the true definition of all profitable Physicke.