A.D. 1751, there was an eruption of Vesuvius; famine and pestilence were rife in the kingdoms of Isen and Cordova; the breaking out of the pestilence being attributed to the arrival of mendicants at the ports of Malaga. The year following, a terrific storm was experienced in Charleston, South Carolina, United States, on the 15th of September, during which the town and neighbourhood were inundated, from which there resulted much loss of life and destruction of property. Two years subsequently, there was an eruption of Vesuvius; and on the 15th of July, a severe earthquake was felt in the Morea: it swallowed up many villages and their inhabitants. Constantinople and Grand Cairo suffered from a similar catastrophe on the 2nd of September; two-thirds of their houses were destroyed, and upwards of 40,000 persons. A mortal distemper seized on cattle in England; 30,000 cows were reported to have died of it in Cheshire alone. From this period until 1760, epidemic pestilence prevailed in various parts of the globe; dysentery of a malignant type in the Northern States of America, malignant fever in Normandy, gangrenous sore-throat in Ireland and France, and a petechial fever in Constantinople, which destroyed 150,000 persons. Famine and plague carried off great numbers in Syria, Smyrna, and Cyprus: in the latter place disease destroyed 30,000 victims; Aleppo, Jerusalem, and Damascus also suffered from epidemic pestilence. In the former place (Aleppo) the winter had been severe, and had destroyed all vegetation; the cold was very intense; the mercury in Fahrenheit’s thermometer, exposed in the open air, sunk entirely into the ball of the tube; millions of olive-trees that had hitherto withstood the blast of fifty winters were blighted, and thousands of persons perished from cold. The failure of the crop in the succeeding harvest occasioned a universal famine with all its attendant miseries. In many places the inhabitants were driven to such extremities, that women ate their own children as soon as they had expired in their arms from the want of nourishment; and numbers of persons from the mountains and adjacent villages came daily to Aleppo to offer their wives and children for sale for a few dollars, to procure a temporary subsistence for themselves, and dogs and human creatures might hourly be seen scratching together on the same dunghill, and contending for a bone or a piece of carrion. Pestilence followed closely on the heels of this famine, which lasted till 1758; 60,000 persons were swept away by it in the city and its environs. Vast numbers of horses during this year died in London and in the neighbourhood from a murrain. Yellow fever of extreme malignity swept the West Indian Islands and the coast of Africa, as recorded by Lind, who describes the mortality to have been produced by a pestilential vapour, which arose in the south-east of the Guinea coast, and traversed immense swamps: in several towns, among the negro population,