A.D. 1745, a murrain broke out amongst the cattle in Turkey, and was succeeded by a dire plague, which raged with great violence, especially in Constantinople. This murrain among the cattle spread and afflicted various parts of Europe; it was very destructive in Switzerland, then diffused itself through Germany, Poland, and Holland, and ultimately reached England: its progress was marked by the appearance of a bluish mist in the atmosphere. Professors Sauvages and Chaumel speak of a murrain as occurring about this period in the Viverais district of France: puerperal fever was epidemic there at the same time. An earthquake destroyed Lima and Callao, in Peru, on the 28th of October; out of 3000 inhabitants at Lima, only one individual escaped. A.D. 1747, a comet was seen; and on the 14th of October the Thames rose to a very great height. In the spring of this year, there broke out in the territory of Huesca of Aragon, an epidemic of malignant catarrh, which was succeeded by petechial fever. In the Asturias, in March, the weather was variable and inclement, and an epidemic icterus, or jaundice, attended with fever of a malignant type, broke out, and continued unto the following May: it caused great mortality. Two hundred thousand of the inhabitants were taken off by pestilence in Constantinople about this time. Dysentery prevailed in various parts of the United States of America, especially at Hartford and Newhaven; yellow fever succeeded, and continued unto the year 1755. A.D. 1748, swarms of locusts settled down in and about London, doing much damage to the vegetation. Two comets were seen this year. A.D. 1750, two earthquakes were experienced in London, the one on the 8th of February, the other a month after, on the 8th of March. The then lord mayor, one alderman, two judges, and the greater part of the jury, with a number of spectators, caught the jail distemper in the month of May at the Old Bailey. About this period, a shock from an earthquake was felt at Philippoli in Romania, by which more than 4000 persons were destroyed. Two years after, in the month of August, 200 mosques and a great part of the city of Adrianople were destroyed by a similar catastrophe.