The year 1819 was marked by great commotions of the elements, and a general spread of epidemic pestilence all over the world; its prevalence was remarked in all the four quarters of the globe, each portion having been visited by the forms of disease peculiar to its several climates. A tract of country, the Ullah-Bund, in the Delta of the Indus, extending nearly fifty miles in length and sixteen in breadth, was upheaved ten feet; while adjoining districts were depressed, and the features of the Delta completely altered. The island of Penang, Sumatra, Singapore, the kingdom of Siam, and the isles of France and Bourbon were infected with pestilential cholera. In the single town of Bankok, the capital of Siam, 40,000 persons perished by this dire destruction. During the year 1820 cholera extended to Tonquin, Cambogia, Cochin-China, Southern China, Canton, the Philippines, &c. A.D. 1821, Xeres was visited by yellow pestilence; the British troops suffered severely, and the civilians in greater proportion; it prevailed also with great destruction at Cadiz, a city which had suffered between the years 1800 and 1821, from eleven epidemic pestilences of a similar type. (_Vide_ Professor Salva, of Barcelona, on Yellow Fever.)--Sir James Fellows, in his reports on the pestilential disorders of Andalusia during these years, asserts, as before remarked, that the air from its stagnant state became so vitiated that its noxious qualities affected even dumb animals. The winter in America this year was mild until the end of December; the spring was wet and cold, and the summer dry and sultry, with uncommon heat; all vegetable productions seemed to wither, and the drought was so great that the wells or springs were dried up; the thermometer rose to 90° and 100° in May; and intermittent, remittent and bilious fevers, with dysenteries, prevailed in the swampy districts. In the month of August, yellow pestilence made its appearance at New York, and was soon rife at Boston, Philadelphia, Baltimore, and at Charleston; it was also prevalent at New Orleans, Natchez, Mobile, Alabama, and the Havannah, and extended along the low banks of the Mississippi river. From this period until 1822, the disease, although diminished in severity, yet carried off great numbers in the various districts.