Destructive cholera, which may be said not to have subsided at all, visited, this year, 1821, the island of Java, Bantam, Mendura, Borneo, and various other parts in the Indian Archipelago. In Java it is reported that 102,000 persons were carried off by it, 17,000 of whom belonged to the town of Batavia, one of the most unhealthy towns in the East. This same year, this dreadful pestilence, in the month of July, reached Muscat in Arabia, in its western course, where 10,000 persons lost their lives, and during the remainder of the year committed great ravages in various places in the Persian Gulf. In the following month, August, it appeared in Persia, and raged with violence at Bassora and at Baghdad. In Bassora, 18,000 lives, being one-third of the population, were sacrificed in eleven days, and a similarly fearful destruction befel Baghdad. In Bushire, where it broke out in July, 1821, its ravages were most fearful. The bazaars were closed, the houses abandoned, the unburied dead lay in heaps in the streets, and the surviving population sought safety in flight. In Shiraz one-eighth of the population perished. In the years 1822–24, it revisited Tonquin and also Pekin, Central and Northern China, the Moluccas or Spice Islands, Amboyna, Macassar, Assam, and most of the other eastern countries. In Ispahan the epidemic did not inflict much damage, but at Erzeroom it attacked the army of the victorious Abbas Mirza, and swept his ranks from front to rear, the terror-stricken soldiery throwing away their arms, and flying from before the invisible destroyer. During these years, 1822–24, extending to 1827–29–30, this pestilence prevailed in many of the principal cities of Persia, and also in Chinese Tartary: it ravaged most of the populous cities of Mesopotamia, Syria, and Judæa, and reached within 150 miles of the Georgian frontiers of Russia: it was also rife at Orenburg and Astrachan, beyond which it seems not to have extended until the years 1828–29, when it appeared at Orenburg, the capital of the province of that name, situated on the Tartar frontier, 400 miles north of the Caspian Sea. During this period, disease was rife in various other parts of the world. There was a great scarcity, A.D. 1822, and epidemic typhus prevailed to a great extent in the west of Ireland, involving other parts of that unfortunate country. An awful earthquake occurred about this period at Chili, by which an immense tract of ground, 1000 square miles, was elevated from two to six feet above its original level, and a great part of the bottom of the sea remained bare and dry at high water, with beds of oysters, mussels, and other shellfish adhering to the rocks on which they grew. The fish being all dead, and exhaling most offensive effluvia, disease consequently ensued. Ordinary typhus prevailed in Paris, during which time many cases of spasmodic yellow fever, as it was termed, were observed.