From October, 1846, to June, 1847, there occurred in the Caucasus and trans-Caucasian provinces no less than 17,055 cases of cholera, of which 6318 died. Astrachan suffered greatly from cholera, great numbers of the inhabitants having been carried off, as was also the case in Moscow. From official accounts received from St. Petersburgh, it appeared the inhabitants of the western town Alexandrof were attacked with cholera, and also the district of Olgapol, in Podolia. The latter is about thirty miles distant from the Austrian frontiers. A.D. 1846 and 1847, an epizootic or murrain destroyed much cattle in Europe, principally oxen; dogs, horses, and sheep suffering comparatively less. Great numbers of horned cattle were destroyed in Wallachia. A kind of pleuro-pneumonia afflicted both men and beasts in various parts of Scotland, principally in East Lothian, as well as in Aberdeenshire, extending throughout the North; it also prevailed in Ayrshire to some extent. In the month of January of the latter year, 1847, influenza prevailed on the coast of Portugal and in the south-east of Spain: it also appeared in Newfoundland and in New Zealand; and in the month of March, in Valparaiso; in April, on the coast of Syria: in July, August, and September, it broke out on the west coast of Africa, south of the equator; during which time (in August) it raged at Hong-Kong. In the month of December, Paris was assailed by this malady, which was also rife at Madrid; it was termed ‘la grippe,’ and seized more than half the population: five thousand persons were said to have been laid up by this wide-spreading disease at one time in Paris. About this period, the island of Java was visited by epidemic diseases. Virulent small-pox committed great havoc, and then typhus prevailed in Ireland; the mortality among the medical profession was great, it being calculated that one-fifteenth of the entire medical community died there during the year. There was great mortality from typhus at Prague, between the 16th of December, 1846, and the 16th of December, 1847; the deaths during that time amounting to 5192. During the latter year, 1847, cholera was rife in Moscow, Stockholm, St. Petersburgh, and Cronstadt; various parts of Europe were visited by influenza, the greater part of the inhabitants of Copenhagen having suffered therefrom: the disease also prevailed at Marseilles, attacking half the population of 80,000 persons; its character, however, was mild.