The sweating sickness again made its appearance, A.D. 1517, in England, having broken out in London, which was crowded with poor. From a scarcity of artizans about this time, it happened that great numbers of foreigners emigrated from Genoa, Lombardy, France, Germany, and Holland to London, and were engaged in the most lucrative branches of employment. This circumstance appears to have increased the prevalent distresses of the lower orders, and a great insurrection of English artizans followed. The popular commotion was, however, soon suppressed without any considerable damage; and Henry VIII., on a solemn day appointed at Westminster for passing judgment upon the prisoners apprehended on the occasion of the riots, bestowed pardon on them, for he saw into the causes of their discontent, and very soon after caused restrictive alien laws to be enacted. The higher classes enjoyed no immunity from this pestilence; their ranks were thinned, and no precaution seemed to avert death from their abodes. Ammonius of Lucca, a scholar of some celebrity, private secretary to the king, was cut off, after having boasted to Sir Thomas More, only a few hours before his death, that by moderation and good management he had secured both his family and himself from disease. Lords Grey and Clinton fell victims to this malady, as did many knights, courtiers, and officers. So rapid and violent was this disease in its course, that it carried off those who were attacked in two or three hours, so that the first shivering fit was the announcement of death; many who were in good health at noon-day were corpses by the evening. This disease arrived at its height about seven weeks after its first appearance, and continued its ravages for six months. Many learned men at Oxford and Cambridge were carried off by this terrible disease, at a time, too, when the sciences were much cultivated and were flourishing. The town of Calais was visited, and, what was very remarkable, none but the English residents there suffered; the Frenchmen enjoyed an immunity from the disease, which did not even spread to any other part of France,--at least there is no account of its having done so. This same year Germany was visited by a brain fever--an epidemic encephalitis. An earthquake caused great destruction in Suabia. Another disease of much more importance appeared in Holland, lasting only eleven days,--an epidemic œsophagitis (diphtherite) it was considered to be, and from its dangerous and inexplicable symptoms it spread terror and horror around; it was so malignant and rapid in its course, that unless assistance was procured within the first eight hours, the patient was past all hope of recovery before the close of the day. Sudden pains in the throat, with violent oppression about the region of the heart, threatened suffocation, and at length actually produced it. From the journal of Tyengius it would appear that this epidemic extended towards the south,