A.D. 1530, the sweating plague raged in Germany, and epidemic scurvy prevailed in Denmark: two years after, various parts of the world were visited by what were called spotted or petechial fevers. In the month of March, pestilence broke out in Aragon and in the city of Saragossa: Italy and Spain suffered also from a gangrenous sore-throat. In October, the Tiber overflowed, and the dykes in Holland were suddenly burst by inundation, to the destruction of much property and of many lives. A.D. 1531. A comet was seen this and the following year. The Tagus overflowed in the month of February, destroying nearly the half of Portugal. Pestilence followed, and devastated several cities, especially Lisbon, as recorded by Cardinal Gastaldi. A.D. 1533, the kingdom of Aragon suffered much from the great want of corn. Amongst the preventive measures taken, was the bull of Pope Adrian VI. against forestallers. Notwithstanding all the measures that were adopted, the want of food (what there was even being of bad quality), with the excessive heat, &c., caused pestilence, which was very fatal, especially in the city of Huesca, and, as it was said, only terminated on the intercession of the Virgin _de los Dolores_. The year following, 1534, the city of Narbonne suffered from plague. Epidemic disease raged in Cork and also in Dresden A.D. 1535. England, the year following, suffered from pestilence, which continued for three years, 1537, 1538, and 1539. Mortal dysentery prevailed all over Europe. In the latter year, the river Lea in England was nearly dried up, and pestilence carried off great numbers in its vicinity. The summer in Europe was so hot, that in many parts the woods took fire spontaneously. The South of Europe was infested with swarms of locusts, and plague was rife in Hungary during the war of the Turks in that country. The famous Ruy Diaz de Isla published this year (1537) one of the best works which had hitherto appeared on the venereal disease. In order to avoid giving offence to any nation by using the popular names, such as the French disease, the Neapolitan, &c., he denominated his work, ‘A Treatise of All Saints against the serpentine disease which came from the Spanish island Hispaniola; a Treatise compiled in the great and famous Hospital of All Saints, in the renowned city of Lisbon.’ Its author, following the opinion prevalent in his time, attributes the origin of this disease to Hispaniola, where the natives call it ‘le llamaban, buainaras, bipas, taynas olias.’ The reason assigned for using the appellation ‘serpentine’ is, because the disease was considered to be analogous to the foulness of that reptile.