_Civis._--“Good wife, the daily jangling and ringing of the bells, the coming in of the minister to every house in ministering the communion, the reading of the homily of death, the digging up of graves, the sparring of windows, and the blazing forth of the blue crosses do make my heart tremble and quake.” A beggar, in the same _Dialogue_, who had arrived from the country, says: “I met with wagones, cartes and horses full loden with yong barnes, for fear of the blacke Pestilence, with them boxes of medicens and sweete perfumes. O God! how fast did they run by hundredes, and were afraied of eche other for feare of smityng.” We get one or two glimpses of this great plague from the medical point of view in Dr John Jones’s _Dyall of Agues_[592]. The worst locality, he says, was “S. Poulkar’s parish [St Sepulchre’s] by reason of many fruiterers, poor people, and stinking lanes, as Turnagain-lane [so called because it led down the slope to Fleet Ditch and ended there], Seacoal-lane, and such other places, there died most in London, and were soonest infected, and longest continued, as twice since I have known London I have marked to be true.” Jones believed in contagion: “I myself was infected by reason that unawares I lodged with one that had it running from him.” His other observation is interesting as proving the possibility of repeated attacks of the buboes in the same person, an observation abundantly confirmed, as we shall see, in the London plagues of 1603 and 1665: “Here now, gentel readers, I think good to admonish all such as have had the plague, that they flie the trust of ignoraunt persons, who use to saye that he who hath once had the plague shal not nede to feare the havinge of it anye more: the whych by this example whyche foloweth (that chaunced to a certayne Bakers wife without Tempel barre in London, Anno Do. 1563) you shall find to be worthelye to be repeated: this sayde wyfe had the plage at Midsommer and at Bartholomewtide, and at Michaelmas, and the first time it brake, the seconde time it brake, but ran littell, the thirde time it appeared and brake not: but she died, notwythstanding she was twyce afore healed.” Two London physicians of some note died of the plague in 1563. One was Dr Geynes, who had brought trouble upon himself by impugning the authority of Galen, perhaps without sufficient reason. Having been cited before the College of Physicians, to whose discipline he was subject, he preferred to recant his heresy rather than undergo imprisonment. He died of plague on 23 July, 1563. Another was Dr John Fryer who had suffered twice for religious heresy, having been imprisoned by queen Mary as a Lutheran, and by queen Elizabeth as a papist. He regained his liberty in August, 1563, but only to die of plague on 21 October, his wife and several of his children having been also victims of the epidemic[593].