Among the oldest German prohibitions against the adulteration of wine is that of Nuremberg in the year 1409; in which however there is no notice taken of litharge. Another of the year 1475 is mentioned by Datt[738]; but some Imperial ones of an earlier period may have been lost[739]. In the year 1487 the emperor caused an order against the adulteration of wine to be published by the governments in Swabia, Franconia and Alsace; and this practice was a subject of deliberation at the diet of Rothenburg the same year, and also at the diet of Worms, under Maximilian I., in 1495. At the diet of Lindau the use of sulphur was in particular prohibited, and also at Freyburg in Brisgau in 1498. In the year 1500 the same affair was discussed at Augsburg, and again at that city in 1548, under Charles V. It appears that this business was left afterwards to the care of the different princes, who from time to time issued prohibitions against so destructive a fraud. Older and severer prohibitions are however to be found in other countries. By an order of William count of Hennegau, Holland and Zeeland, of the year 1327, we find that long before that period it was customary to adulterate wine with noxious and dangerous substances. In the year 1384 the government at Brussels issued a severer order of the like kind, in which vitriol, quicksilver and lapis calaminaris are mentioned[740]. In France we find an old _ordonnance du prevôt de Paris_, for the same purpose, dated September the 20th and December the 2nd, 1371, in which no minerals are mentioned; but in that of 1696 litharge is particularly noticed[741].