Upon lifting the left lobe of the liver, a dark, brownish fluid appeared behind the stomach, the origin of which was not at first apparent. The removal of the liver, however, completely exposing the stomach, showed the posterior wall at the large end, _softened and ruptured_. This softening was evidently a post-mortem action of the gastric juice; the rupture resulting from the tension upon the same, in tearing away the adhesions between the stomach and liver. Upon the removal of the liver, found it to weigh eighteen pounds. The gall-bladder was empty and contracted. The only portion of the gland not involved in the disease, was one of the small lobes, the _lobus Spigelii_, and a portion of the left lobe. Incisions, showed the interior presenting a similar mottled appearance as the surface; dark, almost black spots, intermixed with spots of brown and gray. The blood-vessels of the liver were enlarged, and filled with dark defibrinated blood. No trace of coagulated blood, in any of the blood-vessels of the body. _Microscopic examination._ An examination of a small portion taken from the right lobe, with a power of 350 diameters, showed innumerable cells of an irregular outline, and varying in size; oil globules, and granular matter. The action of acetic acid, rendered the nuclei of the cells faintly visible. Many cells of a large size were found filled with a growth of smaller ones. All other organs of the body normal.[24] CASE II.—_Cancer of the Liver, secondary to Cancer of the Rectum, with diffused Abscess in the Neck._ Mr. A——, of Doylestown, Pa., aged 60, had been suffering for some months with symptoms of disease of the rectum, with also inflammation of the bladder. His passages were painful, and accompanied with more or less bloody, purulent matter. His urine was thick, at first from presence of large quantities of mucus, later of pus. His appetite and digestion were poor; his color pale and cachectic. Some six months previous to death, he commenced passing with his urine, small quantities of seeds of berries, tomatoes, etc. These gradually increased in quantity, until, for some weeks previous to death, there was a free discharge of feculent matter from the bladder, and at the same time much urine passed per rectum. A few days before death, there appeared a diffused swelling upon the front of the neck, extending from the clavicles as high as the upper portion of the larynx. There was no discoloration of the surface. The swelling presented a boggy feel, without any positive fluctuation. On the 15th of July, 1871, I was called by Dr. George Wright, who had been treating the case for the past year, and from whom I learned the above facts, to make a post-mortem examination, the patient having died the day before.