1. The changes induced in the brain substance surrounding tumors are usually, first, derangement of the circulation, and second, as a result of this, effusion of serum, or finally, softening of a greater or lesser amount of contiguous cerebral substance. Head-ache, with epileptic attacks, loss of memory, irregular contraction of the muscles and partial paralysis may accompany the vascular derangement, while as softening or pulpy destruction supervenes, a general aggravation of all the symptoms will follow, ending in death, either with coma or by a sudden apoplectic attack. 2. Tumors of the brain of a _small size_, may be found after death from other causes, that have evidently produced no symptoms during life; and in other instances, they have induced no change until a few days before death, in which cases, the convulsions, paralysis and coma which precedes this result, must be attributed to the vascular disturbance in the surrounding brain tissue. 3. The position of the tumor, will modify to some extent the character of the symptoms manifested. When in the anterior lobes, loss or impairment of speech is said to attend. While, when in the _corpus striatum_, the motions of the legs and arms are disordered. The following are the more commonly recognized tumors of the brain: =Adenoid, or Glandular-like Tumors.= These are generally described as resembling an enlarged lymphatic gland, both in color and density. They may vary in size from a filbert to that of an orange. There may be a single growth of this kind, or several, and they may be found in any part of the brain. =Tubercular or Scrofulous Tumors.= Under this head may be placed certain bodies of a white or pale yellow color, firm, like soft cheese, sometimes granular and friable, and consisting chiefly of a large proportion of albuminous matter. They may be found first, as one or more individual masses of considerable size; or second, sometimes as many minute rounded bodies, distinct and separate from one another. In examining the head of a hydrocephalic child of four years, with Dr. von Tagan, we found attached to the underside of the middle lobe of the left hemisphere, a body of a white cheesy consistence, and of the size of half a hen’s egg. Connected with the cerebellum, was another tumor of the same character, but smaller in size.[6] Tubercular masses of this kind, may be found on the surface, or imbedded in the substance of any portion of the cerebrum or cerebellum. The second form of tubercular deposits, are confined almost wholly to the gray matter of the surface. In one case, over two hundred of these bodies were found scattered through the gray matter of the cerebrum and cerebellum, of the size of a pea or bean, and of a pale yellow or bluish color. When cut open, the interior of the bodies was found to resemble boiled potatoes in consistency.