The time has come, however, when such an astonishing page has been turned in the anti-slavery history of America, that the women of our country, feeling that the great anti-slavery work to which their English sisters exhorted them is almost done, may properly and naturally feel moved to reply to their appeal, and lay before them the history of what has occurred since the receipt of their affectionate and Christian address. Your address reached us just as a great moral conflict was coming to its intensest point. The agitation kept up by the anti-slavery portion of America, by England, and by the general sentiment of humanity in Europe, had made the situation of the slaveholding aristocracy intolerable. As one of them at the time expressed it, they felt themselves under the ban of the civilized world. Two courses only were open to them: to abandon slave institutions, the sources of their wealth and political power, or to assert them with such an overwhelming national force as to compel the respect and assent of mankind. They chose the latter. To this end they determined to seize on and control all the resources of the Federal Government, and to spread their institutions through new States and Territories until the balance of power should fall into their hands, and they should be able to force slavery into all the Free States. A leading Southern senator boasted that he would yet call the roll of his slaves on Bunker Hill; and, for a while, the political successes of the Slave Power were such as to suggest to New England that this was no impossible event. They repealed the Missouri Compromise, which had hitherto stood, like the Chinese wall, between our North-western Territories and the irruptions of slaveholding barbarians. Then came the struggle between Freedom and Slavery in the new Territory,—the battle for Kansas and Nebraska, fought with fire and sword and blood, where a race of men, of whom John Brown was the immortal type, acted over again the courage, the perseverance, and the military religious ardour of the old Covenanters of Scotland, and, like them, redeemed the Ark of Liberty at the price of their own blood, and blood dearer than their own.