Before we pass on to the Fourth Class, we believe it will not be improper to observe, that a very great Number of different Kinds of diseased Persons contained in the preceding, had very moderate Symptoms, whose Force and Malignity appeared to be much less, than in those of the same Accidents daily observed in inflammatory Fevers, or in the most common putrid ones, or in those that are vulgarly called Malignant, if we except the Signs of Fear or Despair, which were Extream, or in the highest Degree; insomuch, that of the great Number of infected Persons who have perished, there were very few, who at the very first Moment of their being seized, did not imagine themselves lost without Relief, whatever Pains we took to encourage them: And though many amongst them seemed to us, before the first Access of the Distemper, to be of a firm and courageous Disposition of Mind, and resolute under all Events, yet as soon as they felt the first Strokes, it was easy to know by their Looks, and their Discourses, that they were convinced that their Sickness was Incurable and Mortal, even at the Time when neither the Pulse, nor the Tongue, nor the Disorder in the Head, nor the Colour of the Face, nor the Disposition of the Mind, nor lastly, the Lesion of any of the other natural Functions mentioned above, gave any fatal Indication, or before there were any Grounds to be allarmed. FOURTH CLASS. The fourth Class contains the Diseased attacked with the same Symptoms with those of the second, but these sorts of Accidents lessened or disappeared the second or third Day of themselves, or in Consequence of the Effects of the internal Remedies, and at the same time in Proportion to the remarkable Eruption of the Buboes and Carbuncles in which the noxious Ferment that was dispersed through the whole Mass, seemed to be collected together; so that the Tumours rising from Day to Day, at length being open, and coming to a Suppuration, the Infected escaped the Danger that threatned them, provided they had some Assistance. These happy Events have determined us to redouble our Care during the whole Course of this Sickness, to accelerate, as much as the State of the Patient will admit, the Eruption, Elevation, Opening, and Suppuration of the Buboes and Carbuncles, in order to free, as soon as possible, by this way, the Mass of Blood, from the fatal Ferment that corrupts it; aiding Nature by a good Regimen, and by such cathartick, cordial, and sudorifick Medicines, as are proper in the present Condition and Temperature of the Sick. FIFTH and LAST CLASS.