The following case is recorded by Sir Astley Cooper:—Mr. Elcock, student of anatomy, slightly punctured his finger in opening the body of a hospital patient about twelve o’clock at noon, and in the evening of the same day, finding the wound painful, showed it to Sir Astley Cooper after his surgical lecture. During the night the pain increased to extremity, and symptoms of high constitutional irritation presented themselves on the ensuing morning. No trace of inflammation was apparent beyond a slight redness of the spot at which the wound had been inflicted, which was a mere puncture. In the evening he was visited by Dr. Babington, in conjunction with Dr. Haighton and Sir Astley Cooper; still no local change was to be discovered, but the nervous system was agitated in a most violent and alarming degree, the symptoms nearly resembling the universal excitation of hydrophobia, and in this state he expired within the period of forty-eight hours from the injury. The late Dr. Pett, of Hackney, being present at the examination of the body of a lady who had died of peritoneal inflammation after her confinement, handled the diseased parts. In the evening of the same day, while at a party, he felt some pain in one of his fingers, on which there was a slight blush, but no wound was visible at that time. The pain increasing, the finger was examined in a stronger light, when, by the aid of a lens, a minute opening in the cuticle was observed. During the night the pain increased to agony, and in the morning his appearance was extremely altered; his countenance was suffused with redness, his eyes were hollow and ferrety; there was a peculiarity in his breathing, which never left him during his illness; his manner, usually gay and playful, was now torpid, like that of a person who had taken an excessive dose of opium, he described himself as having suffered intensely, and said that he was completely knocked down and had not the strength of a child, and he sunk exhausted on the fifth day from the examination of the body. George Higinbottom, an undertaker, was employed to remove in a shell the corpse of a woman who had died of typhus fever in the London Fever Hospital. In conveying the body from the shell into the coffin, he observed that his left hand was besmeared with a moisture which had oozed from it. He had a recent scratch on his thumb. The following morning this scratch was inflamed; in the evening of the same day he was attacked with a cold shivering and pain in his head and limbs, followed the next by other symptoms of severe fever; on the fourth day there was soreness in the top of the shoulder and fulness in the axilla; on the fifth the breast became swollen and efflorescent; on the seventh delirium supervened, succeeded by extreme prostration and coma, and death took place on the tenth day.