Dr. Combe remarks, on this subject, "In the natural and healthy state, under a proper system of diet, and with sufficient exercise, the bowels are relieved regularly, once every day." _Habit_ "is powerful in modifying the result, and in sustaining healthy action when once fairly established. Hence the obvious advantage of observing as much regularity, in relieving the system, as in taking our meals." It is often the case that soliciting Nature at a regular period, once a day, will remedy constipation, without medicine, and induce a regular and healthy state of the bowels. "When, however, as most frequently happens, the constipation arises from the absence of all assistance from the abdominal and respiratory muscles, the first step to be taken, is, again to solicit their aid; first, by removing all impediments to free respiration, such as stays, waistbands and belts; secondly, by resorting to such active exercises, as shall call the muscles into full and regular action; and, lastly, by proportioning the quantity of food to the wants of the system, and the condition of the digestive organs. If we employ these means, systematically and perseveringly, we shall rarely fail in at last restoring the healthy action of the bowels, with little aid from medicine. But if we neglect these modes, we may go on, for years, adding pill to pill, and dose to dose, without ever attaining the end at which we aim." There is no point, in which a woman needs more knowledge and discretion, than in administering remedies for what seem slight attacks, which are not supposed to require the attention of a physician. It is little realized, that purgative drugs are unnatural modes of stimulating the internal organs, tending to exhaust them of their secretions, and to debilitate and disturb the animal economy. For this reason, they should be used as little as possible; and fasting, and perspiration, and the other methods pointed out, should always be first resorted to. When medicine must be given, it should be borne in mind, that there are various classes of purgatives, which produce very diverse effects. Some, like salts, operate to thin the blood, and reduce the system; others are stimulating; and others have a peculiar operation on certain organs. Of course, great discrimination and knowledge is needed, in order to select the kind, which is suitable to the particular disease, or to the particular constitution of the invalid. This shows the folly of using the many kinds of pills, and other quack medicines, where no knowledge can be had of their composition. Pills which are good for one kind of disease, might operate as poison in another state of the system. It is wise to keep always on hand some simple cathartic, for family use, in slight attacks; and always to resort to medical advice, whenever powerful remedies seem to be demanded.[Q] It is very common, in cases of colds which affect the lungs or throat, to continue to try one dose after another, for relief.