To the account of abdominal affection in typhus, it is necessary to add nothing to that already given of abdominal affection in synochus, excepting that, in the former, pain in the abdomen is scarcely ever felt; tenderness on pressure is less acute, and it is more common for both to be absent. On the other hand, the abdomen is more often swollen, hard, tense and tympanitic, while the stools are more early and more constantly passed involuntarily. It is in this type of fever, also, that hæmorrhage from the bowels most frequently takes, place—an event not very uncommon in the severest and the most protracted examples of the disease. The tongue, also, is less constantly red than in the abdominal affection of synochus; but it is more uniformly dry, black and cracked. Since the full exposition of pathology requires that many examples of this affection should be detailed under that head, and since, however numerous and striking such examples may be, they can illustrate no characteristic symptom beyond what has been already stated, it is unnecessary to cite any cases of it here. IV. TYPHUS MITIOR, WITH MIXED AFFECTION. Whenever the brain, the lungs, and the intestines become simultaneously and prominently affected in typhus, the case no longer assumes the mild, but lapses into the severer form. We shall, therefore, speak of this complication under— II. TYPHUS GRAVIOR. The typhus gravior of authors is extinct; at least I have seen no example of it in London. I have witnessed nothing bearing a tolerable resemblance to this disease, even as it is depicted by Cullen, much less as it is portrayed in the darkly vivid, yet apparently but too faithful colouring of Huxham. This malady seems to have disappeared with the epidemic intermittents and the epidemic dysenteries of the good old times. Whatever there may have been in the condition of our ancestors to excite our envy, there is certainly nothing to provoke it in their diseases. All the examples of fever which approach in likeness to the descriptions on record of typhus gravior which I have seen, have consisted of the mixed cases of typhus. They have been cases in which the brain, the lungs, and the intestines were all simultaneously and intensely affected. The symptoms may not always denote an _equal_ degree of affection in all these organs; but I have never seen a case in which there were not the most unequivocal signs of intense affection in all of them. For the reason already assigned, such cases must necessarily be the severest that can occur, because the patient may be said to have three diseases instead of one to contend with, each of which alone is sufficient to destroy life, and each of which alone frequently does destroy it. All the examples of this form of fever which I have observed are referrible to two classes; one in which the arterial action is excessive; the other in which it is oppressed, or rather overwhelmed.