2. The bodily strength entirely fails; the growth of those who have not done growing, and who abandon themselves to this detestable practice, is considerably checked. Some can get no sleep at all, others are in a state of continual dozing. All of them almost become hypochondriacs, or hysteric, and are overwhelmed with all the evils that attend those dreadful disorders; melancholy, sighs, tears, palpitations; suffocations, fainting fits. Some have been known to spit calcarious matter. Coughs, a slow fever, consumptions, are the punishments which some find in their own crimes. 3. The most acute pains are another subject of complaint in the patients. One complains of his head, another of his breast, the stomach, the intestines, aches of external rheumatisms; some are affected with an obtuse sensation of pain in all the parts of the body, on the slightest impression. 4. There are not only to be seen pimples on the face, which is one of the commonest symptoms, but even blotches, or suppurative pustules, on the face, nose, breast, thighs, with cruel itchings on those parts. Nay, one patient complained of fleshy excrescences on his forehead. 5. The organs of generation come in also for their share of the sufferings, of which they are themselves the primary cause. Many patients become incapable of erection; in others, the seminal humor comes away in the moment of the slightest stimulation, and of the weakest erection; some will even evacuate it on going to stool. Numbers are attacked with an habitual gonorrhœa, which intirely destroys constitutional vigor, and the matter of it resembles a fetid _sanies_, or foul mucosity. Others are tormented with painful priapisms. Dysuries, stranguries, heat of urine, a weakening of its spirt, put the patients to cruel inconveniences and pains. Some have very painful tumors in the testicles, in the penis, the bladder, the spermatic string. In short, either the impossibility of coition, or the depravation of the seminal humor, renders incapable of procreation almost all those who have long abandoned themselves to this crime. 6. The functions of the intestines are sometimes totally disordered, and some patients complain of an obstinate costiveness, others of the piles, or of the running of a fetid matter from the fundament. This last observation reminds me of a young man, who, after every act of self-pollution, was attacked with a diarrhœa, which must be an additional cause of a diminution of strength to him. SECTION IV. _The Author’s Observations._ The object of description occurring in my first observation is dreadful; I was myself frighted at the first time of my seeing the unfortunate sufferer, who is the subject of it. Then it was that I felt, more than I had ever before done, the necessity of pointing put to young people, all the horrors of that precipice down which they voluntarily cast themselves.