One of the most constant effects of excessive masturbation is the loss of flesh. This symptom shows itself more or less rapidly, and extends to a greater or less degree. We may regard it as one of the circumstances in which onanists most resemble those affected with phthisis, with diarrhœa, and generally, individuals confined with a severe and long continued illness. The loss of flesh arising from onanism has not unfrequently been attributed to a too precocious growth and vice versa. This symptom is much more striking in some onanists, as it is attended with excessive appetite and a healthy state of the digestive organs. How great must be the influence of the genital organs when abused, on the nutritive process, to cause this loss of flesh, even under the conditions most favorable for its gain. It is not uncommon to see onanists affected with a complete state of marasmus: their frame is reduced to a skeleton and presents in anticipation a picture of the state in which death will soon place them. Many parts, as the loins, thighs and lower extremities are often remarkable for their extreme emaciation. Sainte Marie who has observed this fact, attributes it and also the debility of these parts, to a morbid state of the spinal marrow, and not unjustly. The facility with which onanists regain their flesh on leaving off these bad habits, is equally remarkable with their rapid loss of substance. There are individuals however who remain thin and dried up through life, in consequence of abusing themselves while young.