“Paralysis, during the following years, progressed slowly, but constantly. The arm of the right side lost its motion entirely; the forearm was flexed upon it, and retained this position. At a later period, the fingers became stiff, crooked, and they continued to be so flexed, that a tampon of linen was placed on the palm of the hand, to prevent the nails from lacerating the skin. A singular symptom, also, appeared: if the internal part of the thigh was gently rubbed, the limbs extended quickly, as if by a galvanic shock, and then resumed their first position, which was that of a permanent state of semiflexion. The paralysis finally affected the left upper extremity, which had hitherto been free from it; at the same time, the respiration became more difficult, the voice more feeble, and speech more painful, so that the patient choked, after talking a few moments. These different symptoms, and those described above, gradually became intense; and at the time this case was recorded, the patient was still alive--but in a most lamentable situation. Very severe pains supervened in the right side; the limbs were frequently convulsed; the constipation was obstinate; the urine passed involuntarily; the intellectual faculties, however, remained unaffected; and the patient, who was then fifty years old, proved, by his easy and agreeable conversation, that, notwithstanding his unfortunate situation, he had lost none of his natural gayety of character.” (_Traité de la moelle epinière_, &c., vol. ii., p. 594.) The lower part of the medulla alone was affected in an individual whose case is mentioned by Tissot. In another case related by Weszpremi, the spinal marrow and brain were affected. The patient, who was thirty years old, complained of pains along the spine, especially when he stooped. His legs were so weak, that he could scarcely stand erect for a moment; his memory was considerably weakened, and he seemed stupid; his sight was also affected, and he was extremely thin. This man, having long denied the cause of his disease, finally confessed it. After some months, his health was restored. (_Observ. Med._, p. 175.)