That there are predisposing causes to epidemic disorders, especially to the plague, the most fatal of them all, is not denied. These prepare the body for receiving the infection, but they will not, without that infection, produce the disorder. Of these causes so many are to be found in the conduct of mankind themselves, that we scarcely need to look for them any where else. In looking over the histories of plagues, we find them in an especial manner connected with famines and wars. The former sometimes take place in consequence of the failure of crops through natural causes; but, considering the general fertility of the earth, we must certainly account it owing to bad management, in some respect or other, that every country hath not as much laid up within itself as would guard against the consequences of at least one or two bad crops. Yet we believe there is not, at present, a country upon earth in this predicament. If a crop fails any where, the inhabitants must import largely, or they must starve. This is the case even in the fertile regions of the East, where the earth produces in excessive abundance,[32] and there is little or nothing of any kind of provision exported to other countries. A remarkable instance of this occurred in the plague at Aleppo, a history of which is given by Dr. Russel. He tells us, that the winter of 1756 proved excessively cold, which was followed by a famine next year. This account is confirmed by Mr. Dawes, in a letter to the bishop of Carlisle.[33] He tells us, that in the course of the winter many perished through cold; that the inhabitants were reduced to such extremities, by the single failure of the crop in 1757, that women were known to eat their own children as soon as they expired in their arms with hunger; and that human creatures might be seen contending with dogs, and scratching for the same bone with them in a dunghill. A dreadful plague followed; which, the two succeeding years, swept off not fewer than sixty thousand in the city of Aleppo. [32] Herodotus says, that in his time the province of Babylonia produced commonly two hundred, and in plentiful years three hundred fold. [33] Philos. Transact. vol. liv. It is probable that in this case the famine either produced the plague, or made it worse than it would have otherwise been; and it is not denied that the cold and bad season was the direct cause of the famine. But as little can it be denied, that had the people, or their governors, been so provident as to have laid up stores sufficient to supply the country for one year, this famine would not have been felt. As far, therefore, as the plague was connected with the famine, we must own that it was chargeable on the human race themselves; not the sins of this or that particular person, but a general deviation from the task assigned them by their Maker, viz. that of cultivating the ground; and, instead of this, spending their time in folly and trifling, to say no worse.