In the early part of the nineteenth century, Lancaster in Pennsylvania was the largest inland city of the United States. It is sixty-nine miles from Philadelphia, and the "old Lancaster Road," the finest highway of that period, was constructed to connect them. This began the Pennsylvania route across the Alleghenies to the West, which afterwards became the most travelled. In 1834 the Pennsylvania Government opened its State work, the Columbia Railroad between the Delaware and the Susquehanna. In 1836 there were four daily lines of stages running in connection with this State railroad between Philadelphia and Pittsburg, making the journey in sixty hours. Gradually afterwards the Pennsylvania Railroad was extended across the mountains, and the Baltimore and Ohio Railroad was completed to Wheeling, and they then took away the business from the "Old Pike" and all the other wagon or canal routes to the Ohio River. CHESTER AND LANCASTER VALLEYS. Let us go westward across the Alleghenies by the Pennsylvania route. East of the mountains it traverses a rich agricultural region, limestone valleys, intersected by running streams and enclosed between parallel ridges of hills, stretching, like the mountain ranges, across the country from northeast to southwest. It is a land of prolific farms and dairies, and for miles beyond Philadelphia the line is adjoined by attractive villages and many beautiful suburban villas. Three noted institutions of learning are passed--Haverford College, the great Quaker College, standing in an extensive wooded park; the Roman Catholic Augustinian College at Villa Nova, with its cross-surmounted dome and twin church spires; and the Bryn Mawr College for women, one of the most famous in the United States. This is a region first settled by Welsh Quakers, and the name Bryn Mawr is Welsh for the "great hill." It is a wealthy and extensive settlement, and its College has spacious buildings and over three hundred students. At the Commencements they all join in singing their impressive College hymn: "Thou Gracious Inspiration, our guiding star, Mistress and Mother, all hail Bryn Mawr, Goddess of wisdom, thy torch divine Doth beacon thy votaries to thy shrine, And we, thy daughters, would thy vestals be, Thy torch to consecrate eternally."