Repeated small Doses of the Ipecacuana, from four to six Grains, operated both as an Emetic, and kept up a Purging; but they made the Men so sick, that we could not prevail upon them to continue their Use. Mr. _Francis Russel_ told me, that, in the Year 1756, he found a few Grains of Rhubarb added to each Dose, made it operate more as a Purgative, and did not make the Men so sick.--Dr. _Akenside_ proposes giving the Ipecacuana in so small Doses as one or two Grains every six Hours, in a Draught made of Mint-water, and Half a Drachm of _confectio cardiaca_; and, after bleeding and vomiting once, seems to depend almost entirely on the Use of this Medicine for the Cure of the Dysentery. See his _Comment. de Dysenteria_, cap. 2. The watery Tincture of Rhubarb, recommended by _Degnerus_, we tried in some Cases at Bremen; and found it to be a good mild Purge, but not to answer so well as the Salts and Manna in recent Cases. Mr. _William Russel_ told me that they found this watery Tincture of Rhubarb to answer better in _America_ than any other of the Preparations of Rhubarb. Calomel has been recommended by many as a Purge in Dysenteries; and Dr. _Huxham_ (_de Aere_, Vol. II. P. 100) assures us, that he has often experienced the good Effects of it, especially when the Patient at the same time had Worms; in such Cases we joined it to Rhubarb as mentioned in the Text, or gave a Calomel Bolus over Night, and a Purge next Morning. Dr. _Duncan_, Physician to his Majesty, told me, that he found the following Method of Cure always successful in the Dysentery, which was epidemic in _London_ in the Year 1762. If the Patient was Plethoric, or had much Fever, he ordered more or less Blood to be taken away; and then gave four Ounces of the following Julep, every Half Hour, till it both vomited and purged. ℞ _Tartar. emetic. gr._ iij _Mannæ elect. Unc._ ij _solve in Aq. hordeat. Lib._ 1.--The next Day, and for five or six Days more, the Patient took so much of a Decoction, of Manna, Tamarinds, and soluble Tartar, as kept up a free Discharge by Stool.--If the Irritation and Griping were severe, he found that a Solution of Manna, in the common Almond Emulsion, was sufficient. When the Pain, or Tenesmus, was violent, a Clyster, of Chicken Broth, or of an Infusion of Linseed, with an Ounce or two of Oil of sweet Almonds dissolved in the Yolk of an Egg, injected once or twice a Day, was of great Use. Upon the whole, he was always pleased when he saw large excrementitious Stools come away; and when that could be procured by a gentle Method, he was the more pleased.