If the doctrine of Galvanism have thrown considerable light on various parts of philosophy and chemistry, it gives us reason to hope that it may also be of benefit to medicine. The labours indeed of Galvani, whose most ardent desire was that his discovery might be rendered useful to mankind, were at length directed to this object, and his wishes now begin to be realized; but I must request the reader not to be too sanguine in his expectations, or to imagine that I here mean to entertain him with a long series of wonderful or extraordinary cures performed by means of Galvanism. I have no intention to decorate the discovery of my late uncle with false glory. Though I possess neither the same depth of knowledge, nor the same superiority of talents, I have always endeavoured to imitate his moderation and prudence in the application of his theory. I am fully convinced that much still remains to be done, in order to discover the best methods of employing this new agent; and that the facts respecting it, though numerous, have not been reduced to principles sufficiently certain and satisfactory. There are, nevertheless, some results and observations exceedingly curious, which, if confirmed by new experiments and researches, may enable us to obtain convincing proofs of its utility. New facts, however surprising, are not to be despised merely on account of their being different from any before observed. Those who reject them, as some have done, ought first to show that they are inconsistent with the principles of sound philosophy. Guided by these reflections, and desirous of contributing, as far as possible, towards the illustration of a new and very obscure subject, I shall lay before the reader the result of my researches in the following articles. SECTION I. _Advantages which the medical administration of Galvanism has over that of common electricity._ Several reasons have induced me to prefer the medical administration of Galvanism by means of the pile, to that of artificial electricity. In regard to the action of the common electric machine, the difficulty of calling it forth properly during damp weather; the time required for exciting it; the necessity of charging the jar every time it is applied to the patient, are so many obstacles which render the administration of common electricity inconvenient; and on this account it is now much less used than formerly. On the other hand the pile, according to the observations which I have had an opportunity of making, acts in a uniform manner; is not sensible to the effects of moisture; and forms a sort of Leyden flask, which has a continued action that may be a long time employed. It may be considered as an apparatus, which in itself contains a series of jars charged in succession with different degrees of electricity.