If the Purging therefore continues long after the first Exacerbation of the Disease, it may be look'd upon as a dangerous Symptom; for though it be sometimes restrain'd for the present by Opiates or Astringents, yet it commonly returns with more Vehemence, when their Efficacy ceases, and in a short time exhausts the small Degree of Strength remaining. In this Case they generally spit very little; the _Fauces_ appear dry, glossy, and livid; the external Tumor grows large; they void their Excrements without perceiving it, and fall into profuse Sweats; Respiration becomes difficult and laborious; the extreme Parts grow cold, and Death in a few Hours closes the Scene; and in no Disease that I have seen is the Eye so early deprived of its Lustre as in this; for it is sometimes opake and glassy several Hours before Death; and, as _Ætius Cletus_ hath observed, is a fatal Presage of its Approach. A copious Flux of pituitous Matter to the Glands, and other Parts about the _Fauces_, seem'd to be the Cause of sudden Death, in a Girl about 12 Years old. She was seized in the common Way, with Shivering, Headach, Sickness, Vomiting, and Purging. The Discharges abated in a few Hours, and were succeeded by great Heat, Redness of the Skin, and a sore Throat; the _Uvula_, Tonsils, and, contiguous Parts were red, and so swell'd in eight or ten Hours, as to touch each other, and seem d to close the Entrance into the _Pharynx_. She breath'd without much Difficulty, swallow'd with less Pain than could be imagin'd, and spit up large Quantities of Phlegm. About six in the Evening she was seized with a Difficulty of breathing, as if strangled: Those about her rais'd her up, thinking she was in a Fit; she recover'd herself a little, but expired upon being again laid down in Bed; in somewhat less than 24 Hours from the first Attack. A large Quantity of viscid Phlegm, with which, after she was dead, her Mouth appear to be fill'd, together with the tumefied _Uvula_, Tonsils, and _Velum Palati_, had perhaps jointly closed the _Rima Glottidis_, and put a Stop to Respiration. By a Fall in her Infancy she was reduced to the Necessity of using Crutches. She was big-bon'd, had a good Appetite, and for want of that Exercise, which Persons at her Age commonly enjoy, seem'd to be plethoric. These Circumstances perhaps might contribute to this speedy and unhappy Event. Accidents of the like kind seem not to have been uncommon while this Disease continued in _Italy_, according to a Remark of _Cortesius_[29].