1. That the Sore Throat attended with Ulcers seems to be accompanied with a strong Disposition to Putrefaction, which affects the Habit in general, but the _Fauces_, and the Parts contiguous in particular. And it seems not unreasonable to suppose, 2. That the Cause of this Disposition or Tendency is a putrid _Virus_, or _Miasma sui generis_, introduced into the Habit by Contagion, principally by means of the Breath of the Person, from whom it is received. 3. That this _Virus_, or contagious Matter, produces Effects more or less pernicious, according to the Quantity and Nature of the Infection, and as the Subject is disposed to receive or suffer by it. 4. That putrefactive and malignant Diseases, in common, admit of the most sensible and secure Relief, from Discharges of the peccant Matter, either upon the Skin in general, or on particular Parts of the Body. 5. That the Redness, and cutaneous Efflorescence in the present Case may be consider'd as an Eruption of the like Nature; and therefore to be promoted by such Methods as have proved successful in similar Diseases. 6. That a cordial, alexipharmac, warm Regimen has been found by Experience to be of the most Use in such Cases; and that Bleeding, Purging, Antiphlogistics, liberally employed, either retard, or wholly prevent these Discharges. Therefore, as to expel the morbific Matter (3) seems to be the Design of Nature; to promote this Design by the Measures that are approved by Experience in analogous Disorders, is the Duty of the Physician. It may likewise be remarked, that, though this Disease has now been amongst us several Years, and has consequently survived the different Seasons, and all the Variety of Weather to which we are exposed, yet it seems to shew itself most frequently in Autumn and the Beginning of Winter; at least I have met with many more Cases from _September_ to _December_, inclusive, than in all the other Months together; having not yet seen any who had it in the Spring, and very few in the Summer. It may likewise be remark'd, that the Summers of 1747 and 1748 were dry, with some Days in each uncommonly hot, for this Climate; the Mercury in _Fahrenheit_'s Thermometer rising in the Shade, and within-door, one Day to 78, and during several to 75 and 6. The Autumns of the same Years as unusually temperate and warm; the Wind continuing longer in the Southerly Points than has often been known at this Season. _FINIS._ ----- FOOTNOTES: Footnote 1: Ab Hispanis _Garrotillo_ appellatur, ut eadem patiantur Angina laborantes, quæ facinorosi homines, cum injecto circa collum sune strangulantur. Epist. _R. Moreau_ ad _Th. Barth_. Epist. Med. Cent. i. _p._ 336. Footnote 2: