An anatomical disquisition on the motion of the heart & blood in animalsHarvey, William
Science
An anatomical disquisition on the motion of the heart & blood in animals
Harvey, William
Blood -- Circulation
But lest any one should say that we give them words only, and make
mere specious assertions without any foundation, and desire to
innovate without sufficient cause, three points present themselves for
confirmation, which being stated, I conceive that the truth I contend
for will follow necessarily, and appear as a thing obvious to all.
First,--the blood is incessantly transmitted by the action of the
heart from the vena cava to the arteries in such quantity, that it
cannot be supplied from the ingesta, and in such wise that the whole
mass must very quickly pass through the organ; Second,--the blood
under the influence of the arterial pulse enters and is impelled in
a continuous, equable, and incessant stream through every part and
member of the body, in much larger quantity than were sufficient for
nutrition, or than the whole mass of fluids could supply; Third,--the
veins in like manner return this blood incessantly to the heart from
all parts and members of the body. These points proved, I conceive it
will be manifest that the blood circulates, revolves, propelled and
then returning, from the heart to the extremities, from the extremities
to the heart, and thus that it performs a kind of circular motion.
Let us assume either arbitrarily or from experiment, the quantity of
blood which the left ventricle of the heart will contain when distended
to be, say two ounces, three ounces, one ounce and a half--in the dead
body I have found it to hold upwards of two ounces. Let us assume
further, how much less the heart will hold in the contracted than in
the dilated state; and how much blood it will project into the aorta
upon each contraction;--and all the world allows that with the systole
something is always projected, a necessary consequence demonstrated in
the third chapter, and obvious from the structure of the valves; and
let us suppose as approaching the truth that the fourth, or fifth, or
sixth, or even but the eighth part of its charge is thrown into the
artery at each contraction; this would give either half an ounce, or
three drachms, or one drachm of blood as propelled by the heart at each
pulse into the aorta; which quantity, by reason of the valves at the
root of the vessel, can by no means return into the ventricle. Now,
in the course of half an hour, the heart will have made more than one
thousand beats, in some as many as two, three, and even four thousand.
Multiplying the number of drachms propelled by the number of pulses, we
shall have either one thousand half-ounces, or one thousand times three
drachms, or a like proportional quantity of blood, according to the
amount which we assume as propelled with each stroke of the heart, sent
from this organ into the artery; a larger quantity in every case than
is contained in the whole body! In the same way, in the sheep or dog,
say that but a single scruple of blood passes with each stroke of the
heart, in one half-hour we should have one thousand scruples, or about
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