An Enquiry Into the Origin and Intimate Nature of MalariaWilson, Thomas, active 1795-1858
Science
An Enquiry Into the Origin and Intimate Nature of Malaria
Wilson, Thomas, active 1795-1858
Malaria
Let us not, then, be surprised at the seemingly discordant results
arrived at, and at the contradictory observations which have been
made in the best faith possible, and with every regard to truth in
science. The circumstances which seemed to be identical are merely
analogous, but in point of fact are essentially distinct, as proved
by the results. Changes inappreciable by human sense and as yet by
philosophical instruments, may and no doubt do effect results, to man
seemingly contradictory, simply because he comprehends them not. As
chemical science makes progress, these differences are being reconciled
and understood. Thus, as mere temperature exercises a truly remarkable
influence over the nature of the products of fermentation, may it not
be the efficient cause of the difference we observe between the malaria
of the delta of the Mississippi and that floating near the muddy banks
of the Scheldt? The juice of carrots, beet-root, or onions, which is
rich in sugar, when allowed to ferment at ordinary temperature yields
the same products as grape-sugar, but at a higher temperature the whole
decomposition is changed--there is a much less evolution of gas, and no
alcohol is formed.
In the fermented liquor there is no longer any sugar, and thus may it
be in the great laboratory of nature; the product of the fermentation
will assume in one locality a character it does not possess in another.
The elements are the same; there is merely a change in temperature.
Are there facts to prove that certain states of transformation or
putrefaction in a substance, are likewise propagated to parts or
constituents of the living animal body? Such facts exist. On no other
principle but that of assimilation can we explain the phenomena of
poisoning by the puncture of the living hand in dissecting-rooms, the
instrument being impregnated with a fermentescible and putrefactive
substance, there undergoing a decomposition. Similar, unquestionably,
must be the action of animal poisons, such as that of poisonous
substances, whether animal or vegetable, of the poisons giving rise
to zymotic diseases, &c.; and such may be the origin of the fevers
caused by the unknown principle which must still be connected with
the decomposition of organic bodies most frequently found in marshy
countries. But before entering more fully on this important matter,
I shall first weigh the evidence for and against a theory long
fashionable, and which may even now have its supporters--namely,
whether fermentation or the revolution of higher or more complex
organic vegetable into less complex compounds, be the effect of the
vital manifestations of vegetable matters, and whether putrefaction or
the same change in animal substances be determined by the development
or the presence of animal beings. They who maintain this theory, assume
as a natural consequence of the views that the origin of miasmatic or
contagious diseases, in so far as they may be referred to the presence
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