This Symptom necessarily supposes the Flux of the Spirits thro' the Brain and Nerves in some Measure intercepted or diminished, and consequently as the preceeding may arise from different and even contrary Causes, but generally in these Cases shews a greater Degree of Coagulation in the Juices than the former, and consequently of greater Danger from the more numerous Obstructions in the Capillary and Nervous Vessels. Agreeable to which is that Observation of Dr. _Hodges_, That they who were attended with this Symptom rarely recover'd. [Sidenote: _Trembling, Faultering in the Speech._] These depend on the same Cause as the former, _viz._ On the Diminution or Obstruction of the _Liquidum Nervorum_, whereby the Muscles are involuntarily and weakly contracted. As these suppose a more torpid Motion and greater Viscosity of the Fluids, and less Degree of Elasticity in the solid Parts, so the Method taken herein ought to be more active and stimulating than in any of the foregoing Symptoms. Whence Epispasticks, and the most Volatil Attenuating Medicines are more necessarily required, and ought to be oftner repeated, than in preceeding Symptoms. [Sidenote: _Pain in the Head._] This is Occasioned by the Obstruction of some of the Capillary Vessels of the Brain by the Coagulated Part of the Blood, and the wounding of the Nervous Filaments by the Poisonous Saline _Spiculæ_. Whence the Blood being resisted in its Motion, must press more strongly against the Sides of the Vessels, and distend them beyond their Natural Diameters, and produce a shooting and throbbing Pain; and if the Obstruction continue or increase, a Phrensy, Inflammation, Suppuration, and Gangreen of the Part affected. Why this Symptom should be one of the first, as well as a constant Attendant thro' the whole Course of the Disease, appears from _Prop. 2_. [Sidenote: _Carbuncles, Buboes_, &c.] Hence likewise appears the Reason of Carbuncles, Boboes, Vesications, and the like, which take their Rise from the same Cause, and are different only in Proportion to the Viscosity or Acrimony of the obstructing Matter, and the Situation and Structure of the Part affected. [Sidenote: _Purple spots, Hemorrhages_] These show the greatest Corrosion and Acrimony imaginable in the Circulating Fluids, so as to be able to break and destroy the very Vessels themselves, and consequently certain Signs of a speedy Dissolution of the whole Animal Oeconomy. [Sidenote: _Dissections of such as have died of Malignant and Pestilential diseases._]