The following case was far more severe, but the mode of treatment was not less efficacious. Mr. Granger, aged 36, was exposed to a severe bruise by a great weight of stones which had been piled up, falling upon the outside of the leg; he was extricated from this situation with much difficulty. Besides the bruise, the skin was removed from the outside of the leg to the extent of ten or twelve inches in length, and in some parts an inch and half in breadth; and in the forepart of the ankle a deep furrow was made by the rough edge of one of the stones. I applied the caustic in about half an hour after the accident, over the whole surface of the wounds, and protected the eschar by the gold-beater's skin. The patient was directed to keep the leg cool and exposed to the air. He took no medicine. On the succeeding day the leg was a little swelled, but the patient did not complain of any acute pain but only of a sense of stiffness. An adherent and perfect eschar was found to be formed over the whole extent of the wound. There was no fever. On the third day, the swelling had abated. No further remedy. The patient was still enjoined to rest. On the fourth day the swelling was nearly gone. The eschar remained adherent. The patient walks about. From this time the patient pursued his avocation of a stone-mason; no further remedy was required; no inconvenience experienced; and the eschar separated in about a month. I think it totally impossible to have cured this wound, by any other remedy, in less than a month; during which period the patient must have suffered much pain and fever, and have been quite confined. It is also quite certain, I think, that there would have been an extensive slough, from the severity of the bruise. This was doubtless prevented by the application of the caustic. CASE XVI. J. Jennings, bricklayer, aged 26, fell through the roof of a house and bruised and lacerated his shin rather severely to the extent of an inch and half in one part and in several other places in a less degree. I applied the lunar caustic to the wound immediately. On the following day the eschar was found to be adherent, and there was neither pain nor swelling. The eschars separated in nine days leaving the wounds healed. It is remarkable that the eschar remains a greater or less time over the wound according to the severity and exigency of the case. This case being less severe than the former one the eschar remained upon the wound during a much shorter period of time. CASE XVII. An old man, aged 60, received a bruise upon the occiput from a fall; the skin was lacerated and removed to the extent of half-a-crown. I applied the lunar caustic soon after the accident. On the next day an adherent eschar was formed. There was neither pain nor swelling.--The eschar separated in a fortnight. CASE XVIII.