The Patient, though on the Bed, must, by every Art imaginable, be kept from immediate Sleep, by giving him Wine-Whey, frequently shaking him, and such like Methods, applying to the Nostrils and Temples, Oil of Amber, or other Antispasmodics, such as the Tincture of Assafœtida, Soot, Valerian, &c. and this more or less, as there may be Occasion, by which, and the Power of the Medicines already taken, and the continuing the Use of _Correctors and Nervous Stimulants_, his Sweat will grow profuse, and the Party not so inclinable to Sleep; or, if he should, those Sleeps would not be permanent; which his Attendants should endeavour to prevent, never permitting any one to continue so long as half an Hour at a Time, between Whiles repeating the nervous Medicines, and the Draughts of strong Wine-Whey, in Proportion to such Inclination. If, on the other Hand, the Sleep should be so powerful, as that the Party cannot easily be roused, Blisters must be applied to the Arms. This Process, I persuade myself, will prove sufficient, in the first Instance, where the Opium has been recently taken, especially if the Quantity was not very large, and in such Cases, the Camphire Julip may be very advantageously added to the above Regimen. It is necessary to remember, that an _universal Relaxation_ must be the Consequence of a Conflict of the whole Mechanism; and from these several Evacuations in so small a Space, the human Frame must be weakened, by her Endeavours to extricate herself from the deleterious Effects of this Poison. This Inconvenience is easily repairable, by persevering in the Use of _cordial and bracing Medicines_, which should likewise be continued some Days, to bring the Frame to its pristine State; the Patient must live upon light, but good Nutriment, drink after Meals, in Moderation, of generous Wine, and avoid Sauces with Butter, that all Danger of nervous Tremors, and Loss of Appetite, may be, as much as possible, prevented; but if such should happen to be the Consequence, the Tincture of the _Peruvian_ Bark, with Elixir of Vitriol, in small Doses, will certainly remove them. As I have condemned the Use of Alkalious Medicines, by endeavouring to prove the Impropriety of them, and as the great _Mead_ has mentioned them indefinitely, it may be proper to examine their Antithesis, or contrary Principle of Acids, the Use of which, as Sudorifics and Bracers, to compleat the Cure, are indispensably necessary.