Though it is a received Opinion, that Opium, with us, and other Countries where not manufactured, has not near the Strength of that used by the People where it grows; yet in _Turkey_ they can venture to take it in larger Quantities; and hence it is manifest, that the Effects would be more pernicious amongst them, if they did not use it in a most pure State; and though Habit might conduce to the Constitution bearing it in much larger Doses, than we in _England_ dare give it, yet certainly the constant Use of it, unless when of a most fine Texture of Parts, must sooner prove hurtful, than the immoderate and constant Drinking of Wines, and Spirits; and by this Means, the Lives of the major Part of the Eastern Countries, where it is so much requested, would drop in the Flower of their Youth, and whole Nations, in the Space of a Century, be depopulated. The ancient Accounts of the Manner of gathering Opium, was, according to _Diascorides_, by the milky Juice being collected from Time to Time, that distilled from the wounded Head of the Poppy; thus gathered, it is entirely pure, and being taken, gives no disagreeable Sensation to the Stomach. This Extract being almost wholly volatile, immediately enters into Action, and discharges itself by Perspiration, opening the Pores, and refreshing the Spirits, without any attendant Injury; and daily Experience will convince every one who will put it to the Tryal, that the purer the Opium, in the greater Quantity it may be taken, unattended with the Nausea, Vertigo, and Tremor, which are so often the Consequences of it with us, though used in small Doses. _Tournefort_, Page 292, _Materiæ Medicæ_, informs us, that Opium, or Laudanum, does not only pass off freely by Perspiration, but cures those Distempers arising from Obstructions of the Organs of Respiration in hot Countries, without any Inconvenience whatever, which cannot be said of it, in such Cases, in _England_, though assisted with volatile and cordial Medicines. This seems a palpable Contradiction to the Opinion of Doctor _Jones_, who says, that Opium may be taken in much larger Doses, in Cold, than in hot Climates.