An Essay on the Effects of Opium. Considered as a PoisonAwsiter, John
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An Essay on the Effects of Opium. Considered as a Poison
Awsiter, John
Opium -- Toxicology
Unless Opium were a resinous Body, it could not retain its volatile
Power, to bear transporting in the Form it does, much less endure to be
kept in the Shops with little Loss. The burning of it proves the Truth
of this Assertion, and if it were a mucous Gum, or viscous juice, it
would not flow by Heat, nor import its Strength to a spirituous, but to
an aqueous Menstruum, after the Manner of Gum Arabic. It may be asked
here, in Opposition to this, how the Extract from Opium is made, in
which Process the Opium, according to the College, is ordered to be
dissolved in Water? In Answer to it, I presume, the Water is only an
Agent, that prevents the Adustion of the Parts so exposed to intense
Heat, which Menstruum, being partly imbibed by the Impurities of the
Drug, causes a sufficient Separation, for the resinous Parts to become
soft enough to be pressed through a Bolter; by such Management, the
fæcæs are entirely separated from the purer Parts, and the Water, though
used most cautiously, and in as sparing a Quantity as possible, by the
necessary Evaporation, in order to reduce the pure Body to the former
Substance, loses more than it gains; and after all, in my Opinion, is
not so much to be depended upon, or has so mild an Effect as good Opium;
notwithstanding Doctor _Jones_'s Opinion to the to the contrary, and his
partial Fondness, in giving the Name _Panacea_ to his Solution in Water.
The College of Physicians have ordered only two Preparations that retain
the Name of Opium, wisely considering, that those of the Ancients were
so numerous, and so variously combined with other Substances, under the
Title of Correctors, that the Bulk in administering them was greatly
encreased, and an Inconvenience arose oftentimes to the Patient, who not
being able to take the Quantity of the Opiate required, thereby rendered
the Effect frequently precarious.
One Preparation, directed by them, is by Solution, as mentioned above,
merely to purify it from heterogeneous Particles, and thence called
_Extractum Thebaicum_, or Extract of Opium; the other a Tincture or
Re-Solution of that Extract, to be preserved in a fluid State with Wine,
in the Proportion of two Ounces to one Pound, with an Addition of
Aromatics. This last Preparation, which is in more general Use than the
Extract, is commonly known by the Name of _Laudanum_; though that
Epithet was formerly used by Authors for various Preparations of the
Drug, with the Appendage of Opiatum, Tartarizatum, _&c._ to characterise
their Differences.
I shall not enlarge upon Opium in a physical Sense, further than is
necessary to shew the poisonous Effects of it in over-large Doses, and
as such, I confine myself to the Sort within every one's Knowledge, and
to be commonly met with in the Shops.
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