"In a few days a manifest improvement in health was apparent, his appetite and strength returned, his sleep became more sound and refreshing, and he directly found himself in the enjoyment of better health than he had possessed at any time during ten years of vile submission to a depraved and unnatural appetite. "After abstaining from it about two months, he again, by way of experiment, returned to the cud, cigar, and pipe; and but a few days were requisite to recall all his former dyspeptic symptoms. He again relinquished the habit, under the full conviction that tobacco was the sole cause of his illness, and he firmly resolved never to make further use of it." After recovering a second time from the effects of his poison, this gentleman assured me that, at times, his feelings had bordered on those of mental derangement; he thought every body hated him; and he in turn hated every body. He had often, after lying awake for several hours in the night, under the most distressing forebodings, arisen, smoked his pipe to procure a temporary alleviation of his sufferings, in fitful and half delirious slumbers. He even thought of suicide, but was deterred by the dread of an hereafter. In a few weeks after relinquishing the indulgence, all these feelings were gone; and when I last saw him, about two years, I believe, after quitting his tobacco, he was in fine health and spirits. The following letter from Dr. Moore describes his own case. "_Wells, (Me.) April 10, 1833._ "DEAR SIR,-- "It was not until this late hour, that I received your letter of the 4th inst. With pleasure I hasten to answer your inquiries with regard to my experience in the use of tobacco. "In the autumn of 1817, I commenced (I know not why) the use of tobacco. It was not until the spring of 1825, that I experienced any ill effects from it, except now and then, heart-burn, acid eructations, and occasional fits of melancholy. At that time I became dyspeptic. My food gave me much uneasiness; I had a sinking sensation at the pit of the stomach, wandering pains about the limbs, especially by night, disturbed sleep, loss of appetite, great difficulty of breathing from slight exercise, debility, emaciation, depression of spirits. Such have been my symptoms and feelings the last seven years; and in that time I have had two attacks of haemoptysis, [spitting of blood,] which I attribute solely to the relaxing effects of this narcotic. "The various remedies for dyspepsia were all tried in my case without the least benefit. About the first of December last, I gave up the use of tobacco, and to my astonishment, within the first twenty-four hours, my appetite returned; food gave no uneasiness and strength returned. I have been generally gaining flesh, so that now my weight is greater than it ever was except once.