To prove the power of the mind over the body, Mr Godwin observes, "How often do we find a piece of good news dissipating a distemper? How common is the remark that those accidents which are to the indolent a source of disease are forgotten and extirpated in the busy and active? I walk twenty miles in an indolent and half determined temper and am extremely fatigued. I walk twenty miles full of ardour, and with a motive that engrosses my soul, and I come in as fresh and as alert as when I began my journey. Emotion excited by some unexpected word, by a letter that is delivered to us, occasions the most extraordinary revolutions in our frame, accelerates the circulation, causes the heart to palpitate, the tongue to refuse its office, and has been known to occasion death by extreme anguish or extreme joy. There is nothing indeed of which the physician is more aware than of the power of the mind in assisting or reading convalescence." The instances here mentioned are chiefly instances of the effects of mental stimulants on the bodily frame. No person has ever for a moment doubted the near, though mysterious, connection of mind and body. But it is arguing totally without knowledge of the nature of stimulants to suppose, either that they can be applied continually with equal strength, or if they could be so applied, for a time, that they would not exhaust and wear out the subject. In some of the cases here noticed, the strength of the stimulus depends upon its novelty and unexpectedness. Such a stimulus cannot, from its nature, be repeated often with the same effect, as it would by repetition lose that property which gives it its strength. In the other cases, the argument is from a small and partial effect, to a great and general effect, which will in numberless instances be found to be a very fallacious mode of reasoning. The busy and active man may in some degree counteract, or what is perhaps nearer the truth, may disregard those slight disorders of frame which fix the attention of a man who has nothing else to think of; but this does not tend to prove that activity of mind will enable a man to disregard a high fever, the smallpox, or the plague.